Theranostic chimeric antigen receptor (CAR)-T cells: Insight into recent trends and challenges in solid tumors

K Kheyrolahzadeh, MR Tohidkia, A Tarighatnia… - Life Sciences, 2023 - Elsevier
Cell therapy has reached significant milestones in various life-threatening diseases,
including cancer. Cell therapy using fluorescent and radiolabeled chimeric antigen receptor …

[HTML][HTML] Natural killer cell-derived exosomes for cancer immunotherapy: innovative therapeutics art

Z Hatami, ZS Hashemi, M Eftekhary, A Amiri… - Cancer Cell …, 2023 - Springer
Chimeric antigen receptor natural killer cells (CAR-NK) promote off-the-shelf cellular therapy
for solid tumors and malignancy. However,, the development of CAR-NK is due to their …

[HTML][HTML] NIR fluorescence imaging and treatment for cancer immunotherapy

H Kang, MW Kang, S Kashiwagi… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Cancer immunotherapy has emerged as one of the most powerful anticancer therapies.
However, the details on the interaction between tumors and the immune system are …

Monitoring the cascade of tumor‐specific immune response in vivo via chemoenzymatic proximity labeling

C Liang, J He, X Zhao, J Hong, X Ma… - Angewandte Chemie …, 2023 - Wiley Online Library
Monitoring the highly dynamic and complex immune response remains a great challenge
owing to the lack of reliable and specific approaches. Here, we develop a strategy to monitor …

[HTML][HTML] Tracking adoptive natural killer cells via ultrasound imaging assisted with nanobubbles

Y Jiang, X Hou, X Zhao, J Jing, L Sun - Acta Biomaterialia, 2023 - Elsevier
The recent years has witnessed an exponential growth in the field of natural killer (NK) cell-
based immunotherapy for cancer treatment. As a prerequisite to precise evaluations and on …

Multiparametric MRI for characterization of the tumour microenvironment

E Hoffmann, M Masthoff, WG Kunz… - Nature Reviews …, 2024 - nature.com
Our understanding of tumour biology has evolved over the past decades and cancer is now
viewed as a complex ecosystem with interactions between various cellular and non-cellular …

Multimodal in vivo tracking of chimeric antigen receptor T cells in preclinical glioblastoma models

WE Wu, E Chang, L Jin, S Liu, CH Huang… - Investigative …, 2023 - journals.lww.com
Objectives Iron oxide nanoparticles have been used to track the accumulation of chimeric
antigen receptor (CAR) T cells with magnetic resonance imaging (MRI). However, the only …

[HTML][HTML] Silver nanoclusters show advantages in macrophage tracing in vivo and modulation of anti-tumor immuno-microenvironment

X Yan, Y Qi, L Ren, J Ma, M Xu, T Xia, S Liu - Journal of Controlled Release, 2022 - Elsevier
Macrophage-based nanomedicine represents an emerging powerful strategy for cancer
therapy. Unfortunately, some obstacles and challenges limit the translational applications of …

Present status and future trends in molecular imaging of lymphocytes

C Lauri, M Varani, V Bentivoglio, G Capriotti… - Seminars in Nuclear …, 2023 - Elsevier
Immune system is emerging as a crucial protagonist in a huge variety of oncologic and non-
oncologic conditions including response to vaccines and viral infections (such as SARS …

[HTML][HTML] X-ray-Fluorescence Imaging for In Vivo Detection of Gold-Nanoparticle-Labeled Immune Cells: A GEANT4 Based Feasibility Study

A Ungerer, T Staufer, O Schmutzler, C Körnig… - Cancers, 2021 - mdpi.com
Simple Summary One novel approach in cancer therapy is the use of genetically modified
immune cells that are more specifically directed to a tumor than common chemotherapy …