Diabetes-related pathophysiological alterations and various female reproductive difficulties
were common in pregnant women with gestational diabetes mellitus (GDM), who had 21.1 …

Objective To investigate the expression of short-chain fatty acids (SCFAs)—metabolites of
intestinal flora—in gestational complications of gestational diabetes mellitus (GDM) …

Hemochorial placentas have evolved defense mechanisms to prevent the vertical
transmission of viruses to the immunologically underdeveloped fetus. Unlike somatic cells …

Introduction Preeclampsia (PE) is a serious pregnancy-related complication caused by high
blood pressure in pregnant women. The severe form has more devastating effects …

The HtrA serine peptidase 1 (HTRA1) is a multidomain secretory protein with serine–
protease activity involved in the regulation of many cellular processes in both physiological …

Successful pregnancy establishment requires highly synchronized cross talk between the
invasive trophoblast cells and the receptive maternal endometrium. Any disturbances in this …

Chorioamnionitis generates prostaglandin E 2 and F 2α, promoting fetal membrane rupture,
cervical ripening, and uterine contractions. 15-hydroxyprostaglandin dehydrogenase …

Leptin plays a crucial role in regulating energy homoeostasis, neuroendocrine function,
metabolism, and immune and inflammatory responses. The adipose tissue is a main source …

Argininosuccinate synthase (ASS1) is involved in nitric oxide production, which has a key
role in placental development improving pregnancy outcomes. Syncytiotrophoblast and …

Introduction Embryo implantation is a tightly regulated process, critical for a successful
pregnancy. After attachment of the blastocyst to the surface epithelium of the endometrium …