Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy
PR Williamson, JN Jarvis, AA Panackal… - Nature Reviews …, 2017 - nature.com
HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …
Syndromic panel-based testing in clinical microbiology
P Ramanan, AL Bryson, MJ Binnicker… - Clinical microbiology …, 2018 - Am Soc Microbiol
The recent development of commercial panel-based molecular diagnostics for the rapid
detection of pathogens in positive blood culture bottles, respiratory specimens, stool, and …
detection of pathogens in positive blood culture bottles, respiratory specimens, stool, and …
[HTML][HTML] Single-dose liposomal amphotericin B treatment for cryptococcal meningitis
Background Cryptococcal meningitis is a leading cause of human immunodeficiency virus
(HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a …
(HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a …
Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis
R Rajasingham, RM Smith, BJ Park… - The Lancet infectious …, 2017 - thelancet.com
Background Cryptococcus is the most common cause of meningitis in adults living with HIV
in sub-Saharan Africa. Global burden estimates are crucial to guide prevention strategies …
in sub-Saharan Africa. Global burden estimates are crucial to guide prevention strategies …
[HTML][HTML] Antifungal combinations for treatment of cryptococcal meningitis in Africa
SF Molloy, C Kanyama, RS Heyderman… - … England Journal of …, 2018 - Mass Medical Soc
Background Cryptococcal meningitis accounts for more than 100,000 human
immunodeficiency virus (HIV)–related deaths per year. We tested two treatment strategies …
immunodeficiency virus (HIV)–related deaths per year. We tested two treatment strategies …
[HTML][HTML] Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study
Summary Background WHO recommends Xpert MTB/RIF as initial diagnostic testing for
tuberculous meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about …
tuberculous meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about …
[HTML][HTML] Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis
Background Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency
syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; …
syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; …
Tuberculous meningitis: more questions, still too few answers
GE Thwaites, R van Toorn, J Schoeman - The Lancet Neurology, 2013 - thelancet.com
Tuberculous meningitis is especially common in young children and people with untreated
HIV infection, and it kills or disables roughly half of everyone affected. Childhood disease …
HIV infection, and it kills or disables roughly half of everyone affected. Childhood disease …
HIV-associated opportunistic CNS infections: pathophysiology, diagnosis and treatment
Nearly 30 years after the advent of antiretroviral therapy (ART), CNS opportunistic infections
remain a major cause of morbidity and mortality in HIV-positive individuals. Unknown HIV …
remain a major cause of morbidity and mortality in HIV-positive individuals. Unknown HIV …
Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes
Background. Cryptococcal meningitis (CM) is a leading cause of death in individuals
infected with human immunodeficiency virus (HIV). Identifying factors associated with …
infected with human immunodeficiency virus (HIV). Identifying factors associated with …