Diving into the complexity of the spirochetal endoflagellum
F San Martin, L Fule, G Iraola, A Buschiazzo… - Trends in …, 2023 - cell.com
Spirochaetes, a phylum that includes medically important pathogens such as the causative
agents of Lyme disease, syphilis, and leptospirosis, are in many ways highly unique …
agents of Lyme disease, syphilis, and leptospirosis, are in many ways highly unique …
Questioning rotary functionality in the bacterial flagellar system and proposing a murburn model for motility
Bacterial flagellar system (BFS) was the primary example of a purported 'rotary-
motor'functionality in a natural assembly. This mandates the translation of a circular motion …
motor'functionality in a natural assembly. This mandates the translation of a circular motion …
In situ imaging of bacterial outer membrane projections and associated protein complexes using electron cryo-tomography
M Kaplan, G Chreifi, LA Metskas, J Liedtke, CR Wood… - Elife, 2021 - elifesciences.org
The ability to produce outer membrane projections in the form of tubular membrane
extensions (MEs) and membrane vesicles (MVs) is a widespread phenomenon among …
extensions (MEs) and membrane vesicles (MVs) is a widespread phenomenon among …
CryoEM structures reveal how the bacterial flagellum rotates and switches direction
Bacterial chemotaxis requires bidirectional flagellar rotation at different rates. Rotation is
driven by a flagellar motor, which is a supercomplex containing multiple rings. Architectural …
driven by a flagellar motor, which is a supercomplex containing multiple rings. Architectural …
Discovery of a novel inner membrane-associated bacterial structure related to the flagellar type III secretion system
M Kaplan, CM Oikonomou, CR Wood… - Journal of …, 2022 - Am Soc Microbiol
The bacterial flagellar type III secretion system (fT3SS) is a suite of membrane-embedded
and cytoplasmic proteins responsible for building the flagellar motility machinery …
and cytoplasmic proteins responsible for building the flagellar motility machinery …
Dynamic structural adaptations enable the endobiotic predation of bdellovibrio bacteriovorus
Bdellovibrio bacteriovorus is an endobiotic microbial predator that offers promise as a living
antibiotic for its ability to kill Gram-negative bacteria, including human pathogens. Even after …
antibiotic for its ability to kill Gram-negative bacteria, including human pathogens. Even after …
The connection between Darwin's finches and bacterial flagellar motors
M Kaplan - Physics Today, 2024 - pubs.aip.org
The structure, function, and assembly of the motor have long captured the imagination of
both academic scholars and science popularizers (see the article by Howard Berg, Physics …
both academic scholars and science popularizers (see the article by Howard Berg, Physics …
Applications of Single-Particle Analysis and Cryo-ET in Drug Discovery
Q Yao - Cryo-Electron Microscopy in Structural Biology - taylorfrancis.com
Cryo-electron microscopy (cryo-EM) represents an advanced imaging technique that has
ushered in a revolution in the field of structural biology. This technology has the capability to …
ushered in a revolution in the field of structural biology. This technology has the capability to …