[HTML][HTML] DNA double strand break repair via non-homologous end-joining
AJ Davis, DJ Chen - Translational cancer research, 2013 - ncbi.nlm.nih.gov
DNA double-stranded breaks (DSB) are among the most dangerous forms of DNA damage.
Unrepaired DSBs results in cells undergoing apoptosis or senescence whereas mis …
Unrepaired DSBs results in cells undergoing apoptosis or senescence whereas mis …
Repair of double-strand breaks by end joining
KK Chiruvella, Z Liang… - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Nonhomologous end joining (NHEJ) refers to a set of genome maintenance pathways in
which two DNA double-strand break (DSB) ends are (re) joined by apposition, processing …
which two DNA double-strand break (DSB) ends are (re) joined by apposition, processing …
DNA-PK: a dynamic enzyme in a versatile DSB repair pathway
DNA double stranded breaks (DSBs) are the most cytoxic DNA lesion as the inability to
properly repair them can lead to genomic instability and tumorigenesis. The prominent DSB …
properly repair them can lead to genomic instability and tumorigenesis. The prominent DSB …
Single-molecule imaging reveals how Mre11-Rad50-Nbs1 initiates DNA break repair
DNA double-strand break (DSB) repair is essential for maintaining our genomes. Mre11-
Rad50-Nbs1 (MRN) and Ku70-Ku80 (Ku) direct distinct DSB repair pathways, but the …
Rad50-Nbs1 (MRN) and Ku70-Ku80 (Ku) direct distinct DSB repair pathways, but the …
[PDF][PDF] The contribution of DNA repair pathways to genome editing and evolution in filamentous pathogens
DNA double-strand breaks require repair or risk corrupting the language of life. To ensure
genome integrity and viability, multiple DNA double-strand break repair pathways function in …
genome integrity and viability, multiple DNA double-strand break repair pathways function in …
Pathway choice in DNA double strand break repair: observations of a balancing act
I Brandsma, DC van Gent - Genome integrity, 2012 - Springer
Proper repair of DNA double strand breaks (DSBs) is vital for the preservation of genomic
integrity. There are two main pathways that repair DSBs, Homologous recombination (HR) …
integrity. There are two main pathways that repair DSBs, Homologous recombination (HR) …
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography
LH Thompson - Mutation Research/Reviews in Mutation Research, 2012 - Elsevier
The faithful maintenance of chromosome continuity in human cells during DNA replication
and repair is critical for preventing the conversion of normal diploid cells to an oncogenic …
and repair is critical for preventing the conversion of normal diploid cells to an oncogenic …
Replication protein A: a multifunctional protein with roles in DNA replication, repair and beyond
R Dueva, G Iliakis - NAR cancer, 2020 - academic.oup.com
Single-stranded DNA (ssDNA) forms continuously during DNA replication and is an
important intermediate during recombination-mediated repair of damaged DNA. Replication …
important intermediate during recombination-mediated repair of damaged DNA. Replication …
[HTML][HTML] The multifaceted roles of Ku70/80
S Zahid, M Seif El Dahan, F Iehl… - International Journal of …, 2021 - mdpi.com
DNA double-strand breaks (DSBs) are accidental lesions generated by various endogenous
or exogenous stresses. DSBs are also genetically programmed events during the V (D) J …
or exogenous stresses. DSBs are also genetically programmed events during the V (D) J …
The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage
P Reynolds, JA Anderson, JV Harper… - Nucleic acids …, 2012 - academic.oup.com
DNA double-strand breaks (DSBs) are biologically one of the most important cellular lesions
and possess varying degrees of chemical complexity. The notion that the repairability of …
and possess varying degrees of chemical complexity. The notion that the repairability of …