Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications

S Hong, WA Banks - Brain, behavior, and immunity, 2015 - Elsevier
Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …

Neurochemical evidence of astrocytic and neuronal injury commonly found in COVID-19

N Kanberg, NJ Ashton, LM Andersson, A Yilmaz… - Neurology, 2020 - AAN Enterprises
Objective To test the hypothesis that coronavirus disease 2019 (COVID-19) has an impact
on the CNS by measuring plasma biomarkers of CNS injury. Methods We recruited 47 …

Global HIV neurology: a comprehensive review

KT Thakur, A Boubour, D Saylor, M Das, DR Bearden… - Aids, 2019 - journals.lww.com
Neurological conditions associated with HIV remain major contributors to morbidity and
mortality and are increasingly recognized in the aging population on long-standing …

Cerebrospinal fluid HIV escape from antiretroviral therapy

F Ferretti, M Gisslen, P Cinque, RW Price - Current Hiv/Aids Reports, 2015 - Springer
CNS infection is a nearly constant facet of systemic CNS infection and is generally well
controlled by suppressive systemic antiretroviral therapy (ART). However, there are …

Pharmacokinetics and pharmacodynamics of antiretrovirals in the central nervous system

A Calcagno, G Di Perri, S Bonora - Clinical pharmacokinetics, 2014 - Springer
HIV-positive patients may be effectively treated with highly active antiretroviral therapy and
such a strategy is associated with striking immune recovery and viral load reduction to very …

Neuropathogenesis of HIV-associated neurocognitive disorders: roles for immune activation, HIV blipping and viral tropism

MF Chen, AJ Gill, DL Kolson - Current opinion in HIV and AIDS, 2014 - journals.lww.com
Neuropathogenesis of HIV-associated neurocognitive disorders... : Current Opinion in HIV and
AIDS Neuropathogenesis of HIV-associated neurocognitive disorders: roles for immune …

[HTML][HTML] Temporal patterns and drug resistance in CSF viral escape among ART-experienced HIV-1 infected adults

SS Mukerji, V Misra, D Lorenz… - JAIDS Journal of …, 2017 - journals.lww.com
Background: Cerebrospinal fluid (CSF) viral escape is an increasingly recognized clinical
event among HIV-1-infected adults. We analyzed longitudinal data and drug-resistance …

[HTML][HTML] Highlights of the global HIV-1 CSF escape consortium meeting, 9 June 2016, Bethesda, MD, USA

J Joseph, P Cinque, D Colosi, A Dravid, L Ene… - Journal of virus …, 2016 - Elsevier
CSF HIV escape is a recently recognised phenomenon that suggests that despite
suppressive treatment, HIV RNA may be detected in the CNS compartment in some …

Diffuse white matter signal abnormalities on magnetic resonance imaging are associated with human immunodeficiency virus type 1 viral escape in the central …

R Kugathasan, DA Collier, LJ Haddow… - Clinical Infectious …, 2017 - academic.oup.com
Background. Human immunodeficiency virus type 1 (HIV-1) can replicate independently in
extravascular compartments such as the central nervous system, resulting in either …

[HTML][HTML] Discordant CSF/plasma HIV-1 RNA in individuals on virologically suppressive antiretroviral therapy in Western India

AN Dravid, K Natrajan, MM Kulkarni, CK Saraf… - Medicine, 2018 - journals.lww.com
Discordant CSF/plasma HIV-1 RNA in individuals on virologica... : Medicine Discordant CSF/plasma
HIV-1 RNA in individuals on virologically suppressive antiretroviral therapy in Western India …