An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections

P Zimmermann, N Curtis - Archives of disease in childhood, 2021 - adc.bmj.com
In contrast to other respiratory viruses, children have less severe symptoms when infected
with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this …

Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials

DA Jolliffe, CA Camargo, JD Sluyter… - The lancet Diabetes & …, 2021 - thelancet.com
Background A 2017 meta-analysis of data from 25 randomised controlled trials (RCTs) of
vitamin D supplementation for the prevention of acute respiratory infections (ARIs) revealed …

[HTML][HTML] Role of vitamin D in preventing of COVID-19 infection, progression and severity

N Ali - Journal of infection and public health, 2020 - Elsevier
The outbreak of COVID-19 has created a global public health crisis. Little is known about the
protective factors of this infection. Therefore, preventive health measures that can reduce the …

Quarantine during COVID-19 outbreak: Changes in diet and physical activity increase the risk of cardiovascular disease

AV Mattioli, S Sciomer, C Cocchi, S Maffei… - Nutrition, Metabolism and …, 2020 - Elsevier
Abstract Aims CoV-19/SARS-CoV-2 is a highly pathogenic virus that is causing a global
pandemic with a high number of deaths and infected people. To contain the diffusion of …

Mechanisms in endocrinology: vitamin D and COVID-19

JP Bilezikian, D Bikle, M Hewison… - European journal of …, 2020 - academic.oup.com
The SARS-CoV-2 virus responsible for the COVID-19 pandemic has generated an explosion
of interest both in the mechanisms of infection leading to dissemination and expression of …

Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections

PC Calder, AC Carr, AF Gombart, M Eggersdorfer - Nutrients, 2020 - mdpi.com
Public health practices including handwashing and vaccinations help reduce the spread
and impact of infections. Nevertheless, the global burden of infection is high, and additional …

[HTML][HTML] The link between COVID-19 and VItamin D (VIVID): A systematic review and meta-analysis

A Bassatne, M Basbous, M Chakhtoura, O El Zein… - Metabolism, 2021 - Elsevier
Background Disease severity and mortality rates due to COVID-19 infection are greater in
the elderly and chronically ill patients, populations at high risk for vitamin D deficiency …

[HTML][HTML] Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths

WB Grant, H Lahore, SL McDonnell, CA Baggerly… - Nutrients, 2020 - mdpi.com
The world is in the grip of the COVID-19 pandemic. Public health measures that can reduce
the risk of infection and death in addition to quarantines are desperately needed. This article …

Perspective: Vitamin D deficiency and COVID‐19 severity–plausibly linked by latitude, ethnicity, impacts on cytokines, ACE2 and thrombosis

JM Rhodes, S Subramanian, E Laird… - Journal of internal …, 2021 - Wiley Online Library
Background SARS‐CoV‐2 coronavirus infection ranges from asymptomatic through to fatal
COVID‐19 characterized by a 'cytokine storm'and lung failure. Vitamin D deficiency has …