Cystic fibrosis (CF) is a complex inherited disease which affects many organs, including the
pancreas and liver, gastrointestinal tract and reproductive system, sweat glands and …

Host defense peptides (HDPs) are a large group of innate immune effectors that are also
termed antimicrobial peptides. Because of the rapid progress that has been made in …

Cationic antimicrobial peptides serve as the first chemical barrier between all organisms and
microbes. One of their main targets is the cytoplasmic membrane of the microorganisms …

Currently available antimicrobials exhibit broad killing with regard to bacterial genera and
species. Indiscriminate killing of microbes by these conventional antibiotics can disrupt the …

We study the interaction of antimicrobial peptides with lipopolysaccharide (LPS) bilayers to
understand how antimicrobial peptides interact with the LPS monolayer on the outer …

Antimicrobial peptides (AMPs) are components of complex host secretions, acting
synergistically with other innate defence molecules to combat infection and control resident …

Host‐defense peptides (HPDs) are bactericidal and immunomodulatory molecules, part of
the innate immune system of many organisms, including man. They kill bacteria mostly by …

BurKholderia cepacia complex (Bcc) is a group of phenotypically similar, genetically distinct
bacteria that are beneficial to the environment but can also cause severe human infections …

The properties and structure–activity relationships (SAR) of a macrocyclic analogue of
porcine protegrin I (PG-I) have been investigated. The lead compound, having the sequence …

Both bacteria and the matrix are essential for the development of biofilms. Antimicrobials
should therefore be tested against both components. The aim of this study was to determine …