Interactions between bacterial and phage communities in natural environments

A Chevallereau, BJ Pons, S van Houte… - Nature Reviews …, 2022 - nature.com
We commonly acknowledge that bacterial viruses (phages) shape the composition and
evolution of bacterial communities in nature and therefore have important roles in ecosystem …

The pan-immune system of bacteria: antiviral defence as a community resource

A Bernheim, R Sorek - Nature reviews microbiology, 2020 - nature.com
Viruses and their hosts are engaged in a constant arms race leading to the evolution of
antiviral defence mechanisms. Recent studies have revealed that the immune arsenal of …

[HTML][HTML] Programmable protein delivery with a bacterial contractile injection system

J Kreitz, MJ Friedrich, A Guru, B Lash, M Saito… - Nature, 2023 - nature.com
Endosymbiotic bacteria have evolved intricate delivery systems that enable these organisms
to interface with host biology. One example, the extracellular contractile injection systems …

Mechanisms and clinical importance of bacteriophage resistance

JE Egido, AR Costa… - FEMS microbiology …, 2022 - academic.oup.com
We are in the midst of a golden age of uncovering defense systems against bacteriophages.
Apart from the fundamental interest in these defense systems, and revolutionary applications …

Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

[PDF][PDF] Marine DNA viral macro-and microdiversity from pole to pole

AC Gregory, AA Zayed, N Conceição-Neto… - Cell, 2019 - cell.com
Microbes drive most ecosystems and are modulated by viruses that impact their lifespan,
gene flow, and metabolic outputs. However, ecosystem-level impacts of viral community …

[PDF][PDF] Global trends in marine plankton diversity across kingdoms of life

FM Ibarbalz, N Henry, MC Brandão, S Martini… - Cell, 2019 - cell.com
The ocean is home to myriad small planktonic organisms that underpin the functioning of
marine ecosystems. However, their spatial patterns of diversity and the underlying drivers …

[HTML][HTML] Bacteriophage therapy: clinical trials and regulatory hurdles

LL Furfaro, MS Payne, BJ Chang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Increasing reports of antimicrobial resistance and limited new antibiotic discoveries and
development have fuelled innovation in other research fields and led to a revitalization of …

Phage cocktail development for bacteriophage therapy: toward improving spectrum of activity breadth and depth

ST Abedon, KM Danis-Wlodarczyk, DJ Wozniak - Pharmaceuticals, 2021 - mdpi.com
Phage therapy is the use of bacterial viruses as antibacterial agents. A primary
consideration for commercial development of phages for phage therapy is the number of …

Benzo [a] pyrene stress impacts adaptive strategies and ecological functions of earthworm intestinal viromes

R Xia, M Sun, JL Balcázar, P Yu, F Hu… - The ISME …, 2023 - academic.oup.com
The earthworm gut virome influences the structure and function of the gut microbiome, which
in turn influences worm health and ecological functions. However, despite its ecological and …