Extracellular vesicle-mediated communication within host-parasite interactions

Z Wu, L Wang, J Li, L Wang, Z Wu, X Sun - Frontiers in immunology, 2019 - frontiersin.org
Extracellular vesicles (EVs) are small membrane-surrounded structures released by different
kinds of cells (normal, diseased, and transformed cells) in vivo and in vitro that contain large …

Trichomonas vaginalis: pathogenesis, symbiont interactions, and host cell immune responses

F Mercer, PJ Johnson - Trends in parasitology, 2018 - cell.com
The parasite Trichomonas vaginalis (Tv) causes a highly prevalent sexually transmitted
infection. As an extracellular pathogen, the parasite mediates adherence to epithelial cells to …

Biogenesis of extracellular vesicles in protozoan parasites: The ESCRT complex in the trafficking fast lane?

A Cruz Camacho, D Alfandari, E Kozela… - PLoS …, 2023 - journals.plos.org
Extracellular vesicles (EVs) provide a central mechanism of cell–cell communication. While
EVs are found in most organisms, their pathogenesis-promoting roles in parasites are of …

The Exosome-like Vesicles of Giardia Assemblages A, B, and E Are Involved in the Delivering of Distinct Small RNA from Parasite to Parasite

L Natali, G Luna Pizarro, S Moyano… - International Journal of …, 2023 - mdpi.com
The genetically related assemblages of the intestinal protozoa parasite Giardia lamblia are
morphologically indistinguishable and are often derived from specific hosts. The Giardia …

Trichomonas vaginalis extracellular vesicles are internalized by host cells using proteoglycans and caveolin-dependent endocytosis

AK Rai, PJ Johnson - … of the National Academy of Sciences, 2019 - National Acad Sciences
Trichomonas vaginalis, a human-infective parasite, causes the most prevalent nonviral
sexually transmitted infection worldwide. This pathogen secretes extracellular vesicles (EVs) …

Role of cytoneme structures and extracellular vesicles in Trichomonas vaginalis parasite-parasite communication

N Salas, MB Pedreros, T dos Santos Melo, VG Maguire… - elife, 2023 - elifesciences.org
Trichomonas vaginalis, the etiologic agent of the most common non-viral sexually
transmitted infection worldwide. With an estimated annual prevalence of 276 million new …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor

G Bhatti, R Romero, GE Rice, W Fitzgerald, P Pacora… - PLoS …, 2020 - journals.plos.org
Objective Amniotic fluid cytokines have been implicated in the mechanisms of preterm labor
and birth. Cytokines can be packaged within or on the surface of extracellular vesicles. The …

Modulation of Host-Pathogen Communication by Extracellular Vesicles (EVs) of the Protozoan Parasite Leishmania

G Dong, AL Filho, M Olivier - Frontiers in cellular and infection …, 2019 - frontiersin.org
Leishmania genus protozoan parasites have developed various strategies to overcome host
cell protective mechanisms favoring their survival and propagation. Recent findings in the …

Two Different Species of Mycoplasma Endosymbionts Can Influence Trichomonas vaginalis Pathophysiology

V Margarita, NP Bailey, P Rappelli, N Diaz, D Dessì… - MBio, 2022 - Am Soc Microbiol
Trichomonas vaginalis can host the endosymbiont Mycoplasma hominis, an opportunistic
pathogenic bacterium capable of modulating T. vaginalis pathobiology. Recently, a new …