ABSTRACT A quintessential trait of stem cells is embedded in their ability to self-renew
without incurring DNA damage as a result of genome replication. One key self-renewal …

Protein phosphatase 2, regulatory subunit B (B56), alpha isoform (PPP2R5A) is one of the
regulatory subunits of the protein phosphatase 2A (PP2A), which is a major member of …

Specific niches may affect how cells from different regions contribute to tendon biology,
particularly in regard to the healing of certain tendinopathies. The objectives of this study are …

The epithelial–mesenchymal transition (EMT) is regarded as an important step in cancer
metastasis. Snail, a master regulator of EMT, has been recently proposed to act additionally …

Many metastatic cancers recapitulate the epithelial-to-mesenchymal transition (EMT)
resulting in enhanced cell motility and invasiveness. The EMT is regulated by several …

Stem and progenitor cells maintain a robust DNA replication program during the tissue
expansion phase of embryogenesis. The unique mechanism that protects them from the …

Nucleostemin (NS) is a vertebrate gene preferentially expressed in stem and cancer cells,
which acts to regulate cell cycle progression, genome stability and ribosome biogenesis. NS …

Abstract Ethnopharmacology relevance Danggui Buxue Tang has been used in China to
treat clinical anemia for more than 800 years. However, there is no scientific report on its …

Abstract Objectives: The Nucleostemin (NS) gene encodes a nucleolar protein enriched in
adult and embryonic stem cells. NS is thought to regulate cancer cell proliferation, but the …

Stem cells are endowed with the awesome power of self-renewal and multi-lineage
differentiation that allows them to be major contributors to tissue homeostasis. Owing to their …