New insights into mechanisms of endothelial insulin resistance in type 2 diabetes
J Padilla, C Manrique-Acevedo… - American Journal of …, 2022 - journals.physiology.org
Insulin resistance in the vasculature is a hallmark of type 2 diabetes (T2D), and blunting of
insulin-induced vasodilation is its primary consequence. Individuals with T2D exhibit a …
insulin-induced vasodilation is its primary consequence. Individuals with T2D exhibit a …
Diabetic Endothelial Cell Glycogen Synthase Kinase 3β Activation Induces VCAM1 Ectodomain Shedding
Soluble cell adhesion molecules (sCAMs) are secreted ectodomain fragments of surface
adhesion molecules, ICAM1 and VCAM1. sCAMs have diverse immune functions beyond …
adhesion molecules, ICAM1 and VCAM1. sCAMs have diverse immune functions beyond …
Chronic intermittent hypoxia facilitates the development of angiotensin II-induced abdominal aortic aneurysm in male mice
Obstructive sleep apnea (OSA), characterized by episodes of intermittent hypoxia (IH), is
highly prevalent in patients with abdominal aortic aneurysm (AAA). However, whether IH …
highly prevalent in patients with abdominal aortic aneurysm (AAA). However, whether IH …
Neuraminidase-induced externalization of phosphatidylserine activates ADAM17 and impairs insulin signaling in endothelial cells
L Ferreira-Santos, FI Ramirez-Perez… - American Journal …, 2024 - journals.physiology.org
Endothelial insulin resistance represents a causal factor in the pathogenesis of type 2
diabetes (T2D) and vascular disease, thus the need to identify molecular mechanisms …
diabetes (T2D) and vascular disease, thus the need to identify molecular mechanisms …
[PDF][PDF] Role of Metalloproteinases in Diabetes-associated Mild Cognitive Impairment
VM Pereira, S Pradhanang, JF Prather… - Current … - researchgate.net
Diabetes has been linked to an increased risk of mild cognitive impairment (MCI), a
condition characterized by a subtle cognitive decline that may precede the development of …
condition characterized by a subtle cognitive decline that may precede the development of …