Clinical applications of iron oxide nanoparticles for magnetic resonance imaging of brain tumors
M Iv, N Telischak, D Feng, SJ Holdsworth… - …, 2015 - Taylor & Francis
Current neuroimaging provides detailed anatomic and functional evaluation of brain tumors,
allowing for improved diagnostic and prognostic capabilities. Some challenges persist even …
allowing for improved diagnostic and prognostic capabilities. Some challenges persist even …
[HTML][HTML] Microbeam radiation therapy: Clinical perspectives
MA Grotzer, E Schültke, E Bräuer-Krisch, JA Laissue - Physica Medica, 2015 - Elsevier
Microbeam radiation therapy (MRT), a novel form of spatially fractionated radiotherapy (RT),
uses arrays of synchrotron-generated X-ray microbeams (MB). MRT has been identified as a …
uses arrays of synchrotron-generated X-ray microbeams (MB). MRT has been identified as a …
[HTML][HTML] X-rays can trigger the FLASH effect: Ultra-high dose-rate synchrotron light source prevents normal brain injury after whole brain irradiation in mice
This study is the first proof of concept that the FLASH effect can be triggered by X-rays. Our
results show that a 10 Gy whole-brain irradiation delivered at ultra-high dose-rate with …
results show that a 10 Gy whole-brain irradiation delivered at ultra-high dose-rate with …
Comparative toxicity of synchrotron and conventional radiation therapy based on total and partial body irradiation in a murine model
LML Smyth, JF Donoghue, JA Ventura, J Livingstone… - Scientific reports, 2018 - nature.com
Synchrotron radiation can facilitate novel radiation therapy modalities such as microbeam
radiation therapy (MRT) and high dose-rate synchrotron broad-beam radiation therapy …
radiation therapy (MRT) and high dose-rate synchrotron broad-beam radiation therapy …
A global analysis of viviparity in squamates highlights its prevalence in cold climates
Aim Viviparity has evolved more times in squamates than in any other vertebrate group;
therefore, squamates offer an excellent model system in which to study the patterns, drivers …
therefore, squamates offer an excellent model system in which to study the patterns, drivers …
Toward personalized synchrotron microbeam radiation therapy
Synchrotron facilities produce ultra-high dose rate X-rays that can be used for selective
cancer treatment when combined with micron-sized beams. Synchrotron microbeam …
cancer treatment when combined with micron-sized beams. Synchrotron microbeam …
FLASH and minibeams in radiation therapy: the effect of microstructures on time and space and their potential application to protontherapy
A Mazal, Y Prezado, C Ares, L de Marzi… - The British Journal of …, 2020 - academic.oup.com
After years of lethargy, studies on two non-conventional microstructures in time and space of
the beams used in radiation therapy are enjoying a huge revival. The first effect called …
the beams used in radiation therapy are enjoying a huge revival. The first effect called …
Radiobiological and treatment-related aspects of spatially fractionated radiotherapy
The continuously evolving field of radiotherapy aims to devise and implement techniques
that allow for greater tumour control and better sparing of critical organs. Investigations into …
that allow for greater tumour control and better sparing of critical organs. Investigations into …
Divide and conquer: spatially fractionated radiation therapy
Y Prezado - Expert reviews in molecular medicine, 2022 - cambridge.org
Spatially fractionated radiation therapy (SFRT) challenges some of the classical dogmas in
conventional radiotherapy. The highly modulated spatial dose distributions in SFRT have …
conventional radiotherapy. The highly modulated spatial dose distributions in SFRT have …
[HTML][HTML] Effects of microbeam radiation therapy on normal and tumoral blood vessels
A Bouchet, R Serduc, JA Laissue, V Djonov - Physica Medica, 2015 - Elsevier
Microbeam radiation therapy (MRT) is a new form of preclinical radiotherapy using quasi-
parallel arrays of synchrotron X-ray microbeams. While the deposition of several hundred …
parallel arrays of synchrotron X-ray microbeams. While the deposition of several hundred …