Vitamin D: nutrient, hormone, and immunomodulator

F Sassi, C Tamone, P D'Amelio - Nutrients, 2018 - mdpi.com
The classical functions of vitamin D are to regulate calcium-phosphorus homeostasis and
control bone metabolism. However, vitamin D deficiency has been reported in several …

Steroid biosynthesis in adipose tissue

J Li, V Papadopoulos, V Vihma - Steroids, 2015 - Elsevier
Tissue-specific expression of steroidogenic enzymes allows the modulation of active steroid
levels in a local manner. Thus, the measurement of local steroid concentrations, rather than …

Vitamin D in atherosclerosis and cardiovascular events

F Carbone, L Liberale, P Libby… - European heart …, 2023 - academic.oup.com
Both experimental and clinical findings linking vitamin D to cardiovascular (CV) risk have
prompted consideration of its supplementation to improve overall health. Yet several meta …

Influences of vitamin D and iron status on skeletal muscle health: A narrative review

ME Shoemaker, OF Salmon, CM Smith… - Nutrients, 2022 - mdpi.com
There is conflicting evidence of the roles vitamin D and iron have in isolation and combined
in relation to muscle health. The purpose of this narrative review was to examine the current …

Epicardial adipose tissue GLP-1 receptor is associated with genes involved in fatty acid oxidation and white-to-brown fat differentiation: a target to modulate …

E Dozio, E Vianello, AE Malavazos, L Tacchini… - International journal of …, 2019 - Elsevier
Background Epicardial adipose tissue (EAT) is a risk factor for cardiovascular diseases.
Glucagon-like peptide 1 analogs (GLP-1A) may have beneficial cardiovascular effects and …

Irisin: a potential link between physical exercise and metabolism—an observational study in differently trained subjects, from elite athletes to sedentary people

S Benedini, E Dozio, PL Invernizzi… - Journal of Diabetes …, 2017 - Wiley Online Library
We compared irisin levels among groups of differently trained healthy individuals to explore
the role of irisin as a physiological linker between exercise and metabolic health. Irisin and …

Vitamin D deficiency accelerates coronary artery disease progression in swine

S Chen, VJ Swier, CS Boosani… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—The role of vitamin D deficiency in coronary artery disease (CAD) progression is
uncertain. Chronic inflammation in epicardial adipose tissue (EAT) has been implicated in …

Aging, low-grade systemic inflammation and vitamin D: a mini-review

CMR Gonçalves de Carvalho… - European journal of clinical …, 2017 - nature.com
We conducted a mini-review of the literature, focusing on aging-related systemic
inflammation and its association with vitamin D (VitD). As main findings, data indicate that …

Vitamin D and macrophage polarization in epicardial adipose tissue of atherosclerotic swine

P Gunasekar, VJ Swier, JP Fleegel, CS Boosani… - PLoS …, 2018 - journals.plos.org
Vitamin D functions as a potent immunomodulator by interacting with many immune cells
however, its role in regulating inflammation in the epicardial adipose tissue (EAT) is unclear …

Relationship between soluble receptor for advanced glycation end products (sRAGE), body composition and fat distribution in healthy women

E Dozio, S Briganti, A Delnevo, E Vianello… - European journal of …, 2017 - Springer
Purpose Soluble receptor for advanced glycation end products (sRAGE) is a decoy receptor
which sequesters RAGE ligands and acts as a cytoprotective agent. To date, it is unclear …