Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Tumor-induced osteomalacia (TIO) is an ultrarare paraneoplastic syndrome due to
overproduction of fibroblast growth factor 23 (FGF23), with profound effects on patient …

The ageing suppressor α-klotho binds to the fibroblast growth factor receptor (FGFR). This
commits FGFR to respond to FGF23, a key hormone in the regulation of mineral ion and …

Rationale: Cardiac aging is an important contributing factor for heart failure, which affects a
large population but remains poorly understood. Objective: The purpose of this study is to …

Fibroblast growth factor 23 (FGF23) is a phosphotropic hormone that belongs to a subfamily
of endocrine FGFs with evolutionarily conserved functions in worms and fruit flies. FAM20C …

Circulating levels of fibroblast growth factor 23 (FGF23) are elevated in patients with chronic
kidney disease (CKD), but the mechanisms are poorly understood. Here we tested whether …

Background X-linked hypophosphatemia (XLH) is an inherited disease of phosphate
metabolism in which inactivating mutations of the Phosphate Regulating Endopeptidase …

Abstract Fibroblast growth factor 23 (FGF23) was initially characterized as an important
regulator of phosphate and calcium homeostasis. New research advances demonstrate that …

The discovery of the Klotho (KL) gene, which was originally identified as a putative aging-
suppressor gene, has generated tremendous interest and has advanced understanding of …

Regulated fibroblast growth factor (FGF) signalling is a prerequisite for the correct
development and homeostasis of articular cartilage, as evidenced by the fact that aberrant …