Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Parkinson's disease (PD) is a complex, multi-system neurodegenerative disorder. The
second most common neurodegenerative disorder after Alzheimer's disease, it affects …

Here we argue functional neuroanatomy for posture-gait control. Multi-sensory information
such as somatosensory, visual and vestibular sensation act on various areas of the brain so …

For the last two decades, pathogenic concepts in Parkinson disease (PD) have revolved
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …

Abstract Purpose of Review The sense of smell is today one of the focuses of interest in
aging and neurodegenerative disease research. In several neurodegenerative diseases …

Parkinson's disease (PD) is a neurodegenerative disorder that affects millions of people
worldwide. Two hallmarks of PD are the accumulation of alpha‐synuclein and the loss of …

The lateral part of the mesopontine tegmentum contains functionally important structures
involved in the control of posture and gait. Specifically, the mesencephalic locomotor region …

Parkinson's disease involves multiple neurotransmitter systems beyond the classical
dopaminergic circuit, but their influence on structural and functional alterations is not well …

Freezing of gait (FOG) is a common and debilitating, but largely mysterious, symptom of
Parkinson disease. In this review, we will discuss the cerebral substrate of FOG focusing on …

Current research efforts on neurological diseases are focused on identifying novel disease
biomarkers to aid in diagnosis, provide accurate prognostic information and monitor disease …