Background Synthetic cannabinoids (SC) are a heterogeneous group of compounds
developed to probe the endogenous cannabinoid system or as potential therapeutics …

Studies using animal models of adolescent exposure to alcohol, nicotine, cannabinoids, and
the stimulants cocaine, 3, 4-methylenedioxymethampethamine and methamphetamine have …

This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Recent attention has been focused on the long-term impact of cannabis exposure, for which
experimental animal studies have validated causal relationships between neurobiological …

Adolescence is a critical phase of active brain development often characterized by the
initiation of marijuana (Cannabis sativa) use. Limited information is known regarding the …

The adolescent brain is a period of dynamic development making it vulnerable to
environmental factors such as drug exposure. Of the illicit drugs, cannabis is most used by …

Despite the high prevalence of marijuana use among pregnant women and adolescents, the
impact of cannabis on the developing brain is still not well understood. However, growing …

Adolescence represents a critical period for brain development and the endocannabinoid
system plays a crucial role in the regulation of neuronal refinement during this period …

Recreational and chronic cannabis use has been associated with a range of acute and
chronic effects including; anti‐nociceptive actions, anxiety, depression, psychotic symptoms …

This review focuses on the endocannabinoid system as a crucial player during critical
periods of brain development, and how its disturbance either by early life stressful events or …