Background A century after its discovery, Chagas disease still represents a major neglected
tropical threat. Accurate diagnostics tools as well as surrogate markers of parasitological …

Background The analytical validation of sensitive, accurate and standardized Real-Time
PCR methods for Trypanosoma cruzi quantification is crucial to provide a reliable laboratory …

Background This report describes a real-time PCR (Q-PCR) strategy to quantify
Trypanosoma cruzi (T. cruzi) DNA in peripheral blood samples from Chagas disease …

Although the genome of Trypanosoma cruzi, the causative agent of Chagas disease, was
first made available in 2005, with additional strains reported later, the intrinsic genome …

Repetitive DNA elements have been a part of the genomic fauna of eukaryotes perhaps
since their very beginnings. Millions of years of coevolution have given repeats central roles …

Trypanosoma cruzi is the causative agent of Chagas disease, which affects more than 9
million people in Latin America. We have generated a draft genome sequence of the TcI …

A novel large multigene family was recently identified in the human pathogen Trypanosoma
cruzi, causative agent of Chagas disease, and corresponds to∼ 6% of the parasite diploid …

Background The diagnosis of Chagas disease is complex due to the dynamics of
parasitemia in the clinical phases of the disease. The molecular tests have been considered …

Chagas' disease caused by Trypanosoma cruzi is endemic in Latin America. T. cruzi
presents heterogeneous populations and comprises two main genetic lineages, named T …

Background Trypanosoma rangeli is a hemoflagellate protozoan parasite infecting humans
and other wild and domestic mammals across Central and South America. It does not cause …