Cell death mediated by the pyroptosis pathway with the aid of nanotechnology: prospects for cancer therapy
Pyroptosis, a unique form of programmed cell death (PCD) that is characterized by DNA
fragmentation, chromatin condensation, cellular swelling with big bubbles, and leakage of …
fragmentation, chromatin condensation, cellular swelling with big bubbles, and leakage of …
Understanding nanomaterial–liver interactions to facilitate the development of safer nanoapplications
Nanomaterials (NMs) are widely used in commercial and medical products, such as
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …
[HTML][HTML] A pyroptosis nanotuner for cancer therapy
B Chen, Y Yan, Y Yang, G Cao, X Wang… - Nature …, 2022 - nature.com
Pyroptosis is a gasdermin-mediated programmed necrosis that occurs via membrane
perforation and that can be exploited for biomedical applications in cancer therapy …
perforation and that can be exploited for biomedical applications in cancer therapy …
The nano–bio interactions of nanomedicines: understanding the biochemical driving forces and redox reactions
Conspectus Engineered nanomaterials (ENMs) have been developed for imaging, drug
delivery, diagnosis, and clinical therapeutic purposes because of their outstanding …
delivery, diagnosis, and clinical therapeutic purposes because of their outstanding …
Emerging pyroptosis-engineered nanobiotechnologies regulate cancers and inflammatory diseases: A double-edged sword
Y Zhang, C Fang, W Zhang, K Zhang - Matter, 2022 - cell.com
Pyroptosis is closely associated with tumors and inflammatory diseases. By enhancing
pyroptosis, direct and immune-response-triggered deaths of tumor cells are increased …
pyroptosis, direct and immune-response-triggered deaths of tumor cells are increased …
Nanoparticle-induced ferroptosis: detection methods, mechanisms and applications
Although ferroptosis is an iron-dependent cell death mechanism involved in the
development of some severe diseases (eg, Parkinsonian syndrome, stroke and tumours) …
development of some severe diseases (eg, Parkinsonian syndrome, stroke and tumours) …
Nanomedicine‐enabled/augmented cell pyroptosis for efficient tumor nanotherapy
The terrible morbidity and mortality of malignant tumors urgently require innovative
therapeutics, especially for apoptosis‐resistant tumors. Pyroptosis, a pro‐inflammatory form …
therapeutics, especially for apoptosis‐resistant tumors. Pyroptosis, a pro‐inflammatory form …
Polystyrene nanoparticle exposure supports ROS-NLRP3 axis-dependent DNA-NET to promote liver inflammation
Q Chi, T Xu, Y He, Z Li, X Tang, X Fan, S Li - Journal of Hazardous Materials, 2022 - Elsevier
The widespread use of plastics and the rapid development of nanotechnology bring
convenience to our lives while also increasing the environmental burden and increasing the …
convenience to our lives while also increasing the environmental burden and increasing the …
[HTML][HTML] Toxicity of manufactured nanomaterials
Manufactured nanomaterials with unique properties have been extensively applied in
various industrial, agricultural or medical fields. However, some of the properties have been …
various industrial, agricultural or medical fields. However, some of the properties have been …
Nanoceria, the versatile nanoparticles: Promising biomedical applications
Nanotechnology has been a boon for the biomedical field due to the freedom it provides for
tailoring of pharmacokinetic properties of different drug molecules. Nanomedicine is the …
tailoring of pharmacokinetic properties of different drug molecules. Nanomedicine is the …