Non-alcoholic fatty liver disease (NAFLD) has become one of the most common forms of
chronic liver disease worldwide and its prevalence is expected to continue rising. NAFLD …

It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …

Aims: The N6-methyladenosine (m 6 A) modification plays an important role in various
biological processes, but its role in atherosclerosis remains unknown. The aim of this study …

Intake of hemoglobin by the hemoglobin-haptoglobin receptor CD163 leads to a distinct
alternative non–foam cell antiinflammatory macrophage phenotype that was previously …

Plaque microvascularization and increased endothelial permeability are key players in the
development of atherosclerosis, from the initial stages of plaque formation to the occurrence …

New vessel formation inside the arterial wall and atherosclerotic plaques plays a critical role
in pathogenesis of heart attacks and strokes. The 2 known mechanisms resulting in the …

Significance: Reactive oxygen species (ROS) play a critical role in vascular disease. While
there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate …

Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

There are several well-documented functions of high-density lipoprotein (HDL) that may
explain the ability of these lipoproteins to protect against atherosclerosis. The best …

One early phase of atherosclerosis involves the recruitment of inflammatory cells from the
circulation and their transendothelial migration. This process is predominantly mediated by …