Acute graft-versus-host disease—biologic process, prevention, and therapy
When T cells from a bone marrow donor begin to attack the host within 3 months after
hematopoietic-cell transplantation, acute graft-versus-host disease results. The disease …
hematopoietic-cell transplantation, acute graft-versus-host disease results. The disease …
EBMT/ESID inborn errors working party guidelines for hematopoietic stem cell transplantation for inborn errors of immunity
AC Lankester, MH Albert, C Booth… - Bone Marrow …, 2021 - nature.com
Inborn errors of immunity (IEI) are a group of rare heterogeneous diseases. Currently, more
than 400 monogenetic IEI have been identified and increasingly a genetic diagnosis can be …
than 400 monogenetic IEI have been identified and increasingly a genetic diagnosis can be …
Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019
This is the seventh special EBMT report on the indications for haematopoietic stem cell
transplantation for haematological diseases, solid tumours and immune disorders. Our aim …
transplantation for haematological diseases, solid tumours and immune disorders. Our aim …
Lentiviral gene therapy for X-linked chronic granulomatous disease
Chronic granulomatous disease (CGD) is a rare inherited disorder of phagocytic cells,. We
report the initial results of nine severely affected X-linked CGD (X-CGD) patients who …
report the initial results of nine severely affected X-linked CGD (X-CGD) patients who …
A review of chronic granulomatous disease
DE Arnold, JR Heimall - Advances in therapy, 2017 - Springer
Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by defects in
any of the five subunits of the NADPH oxidase complex responsible for the respiratory burst …
any of the five subunits of the NADPH oxidase complex responsible for the respiratory burst …
Primary immunodeficiency and autoimmunity: a comprehensive review
The primary immunodeficiency diseases (PIDs) include many genetic disorders that affect
different components of the innate and adaptive responses. The number of distinct genetic …
different components of the innate and adaptive responses. The number of distinct genetic …
Hematopoietic stem cell transplantation in primary immunodeficiency diseases: current status and future perspectives
Primary immunodeficiencies (PID) are disorders that for the most part result from mutations
in genes involved in immune host defense and immunoregulation. These conditions are …
in genes involved in immune host defense and immunoregulation. These conditions are …
Chronic granulomatous disease: a comprehensive review
Chronic granulomatous disease (CGD) is a primary immunodeficiency of phagocyte function
due to defective NADPH oxidase (phox). Compared with the common types of CYBB/gp91 …
due to defective NADPH oxidase (phox). Compared with the common types of CYBB/gp91 …
Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort …
IH Bartelink, A Lalmohamed, EML van Reij… - The Lancet …, 2016 - thelancet.com
Background Intravenous busulfan combined with therapeutic drug monitoring to guide
dosing improves outcomes after allogeneic haemopoietic cell transplantation (HCT). The …
dosing improves outcomes after allogeneic haemopoietic cell transplantation (HCT). The …
Hematopoietic cell transplantation in chronic granulomatous disease: a study of 712 children and adults
R Chiesa, J Wang, HJ Blok, S Hazelaar… - Blood, The Journal …, 2020 - ashpublications.org
Chronic granulomatous disease (CGD) is a primary immunodeficiency resulting in life-
threatening infections and inflammatory complications. Allogeneic hematopoietic cell …
threatening infections and inflammatory complications. Allogeneic hematopoietic cell …