Pattern recognition receptors in health and diseases

D Li, M Wu - Signal transduction and targeted therapy, 2021 - nature.com
Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …

Cross-talk between alveolar macrophages and lung epithelial cells is essential to maintain lung homeostasis

EY Bissonnette, JF Lauzon-Joset, JS Debley… - Frontiers in …, 2020 - frontiersin.org
The main function of the lung is to perform gas exchange while maintaining lung
homeostasis despite environmental pathogenic and non-pathogenic elements contained in …

[HTML][HTML] In vitro evaluation of nanoplastics using human lung epithelial cells, microarray analysis and co-culture model

S Yang, Y Cheng, Z Chen, T Liu, L Yin, Y Pu… - … and environmental safety, 2021 - Elsevier
Nanoplastics, including polystyrene nanoplastics (PS-NPs), are widely existed in the
atmosphere, which can be directly and continuously inhaled into the human body, posing a …

Pulmonary surfactant: a mighty thin film

F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Opsonins and dysopsonins of nanoparticles: facts, concepts, and methodological guidelines

E Papini, R Tavano, F Mancin - Frontiers in immunology, 2020 - frontiersin.org
Understanding the effects mediated by a set of nanoparticle (NP)-bound host biomolecules,
often indicated with the umbrella term of NP corona, is essential in nanomedicine …

Force field and a surface model database for silica to simulate interfacial properties in atomic resolution

FS Emami, V Puddu, RJ Berry, V Varshney… - Chemistry of …, 2014 - ACS Publications
Silica nanostructures find applications in drug delivery, catalysis, and composites, however,
understanding of the surface chemistry, aqueous interfaces, and biomolecule recognition …

Rationale for targeting complement in COVID‐19

A Polycarpou, M Howard, CA Farrar… - EMBO molecular …, 2020 - embopress.org
A novel coronavirus, SARS‐CoV‐2, has recently emerged in China and spread
internationally, posing a health emergency to the global community. COVID‐19 caused by …

Prolyl 4-hydroxylase

KL Gorres, RT Raines - Critical reviews in biochemistry and …, 2010 - Taylor & Francis
Posttranslational modifications can cause profound changes in protein function. Typically,
these modifications are reversible, and thus provide a biochemical on-off switch. In contrast …

Alveolar-capillary membrane-related pulmonary cells as a target in endotoxin-induced acute lung injury

Z Nova, H Skovierova, A Calkovska - International Journal of Molecular …, 2019 - mdpi.com
The main function of the lungs is oxygen transport from the atmosphere into the blood
circulation, while it is necessary to keep the pulmonary tissue relatively free of pathogens …

An integrated view of humoral innate immunity: pentraxins as a paradigm

B Bottazzi, A Doni, C Garlanda… - Annual review of …, 2009 - annualreviews.org
The innate immune system consists of a cellular and a humoral arm. Pentraxins (eg, the
short pentraxin C reactive protein and the long pentraxin PTX3) are key components of the …