Recent trends, challenges and future outlook of transdermal drug delivery systems for rheumatoid arthritis therapy

M Qindeel, MH Ullah, N Ahmed - Journal of Controlled Release, 2020 - Elsevier
At present, several drug molecules have been used for the treatment of rheumatoid arthritis
(RA). However, the utilization of these compounds through the oral and parenteral route is …

[HTML][HTML] Potential of nanoparticulate carriers for improved drug delivery via skin

A Zeb, ST Arif, M Malik, FA Shah, FU Din… - Journal of …, 2019 - Springer
Skin as a delivery route for drugs has attracted a great attention in recent decades as it
avoids many of the limitations of oral and parenteral administration. However, the excellent …

Transfersomes: a revolutionary nanosystem for efficient transdermal drug delivery

MW Akram, H Jamshaid, FU Rehman, M Zaeem… - AAPS …, 2022 - Springer
Transdermal delivery system has gained significance in drug delivery owing to its
advantages over the conventional delivery systems. However, the barriers of stratum …

Macrophage targeting with the novel carbopol-based miltefosine-loaded transfersomal gel for the treatment of cutaneous leishmaniasis: in vitro and in vivo analyses

S Batool, F Zahid, F Ud-Din, SS Naz… - Drug development …, 2021 - Taylor & Francis
Objective The purpose of this study was to develop novel carbopol-based miltefosine-
loaded transfersomal gel (HePCTG) for the treatment of cutaneous leishmaniasis (CL) via …

Topical delivery of curcumin-loaded transfersomes gel ameliorated rheumatoid arthritis by inhibiting NF-κβ pathway

E Sana, M Zeeshan, QU Ain, AU Khan, I Hussain… - …, 2021 - Taylor & Francis
Aim: To fabricate and evaluate curcumin-loaded transfersomes (Cur-TF) for the targeted
delivery and enhanced therapeutic efficacy of curcumin for the treatment of rheumatoid …

[HTML][HTML] Investigation of the phytochemical composition, antioxidant, antibacterial, anti-osteoarthritis, and wound healing activities of selected vegetable waste

MA Salem, OG Mohamed, EM Mosalam, AI Elberri… - Scientific reports, 2023 - nature.com
Agri-food wastes, produced following industrial food processing, are mostly discarded,
leading to environmental hazards and losing the nutritional and medicinal values associated …

[HTML][HTML] Hydrogel containing solid lipid nanoparticles loaded with argan oil and simvastatin: Preparation, in vitro and ex vivo assessment

MFA Khan, A Ur. Rehman, H Howari, A Alhodaib… - Gels, 2022 - mdpi.com
Transdermal hydrogels have the potential to improve therapeutic outcomes via enhancing
bioavailability and reducing toxicity associated with oral delivery. The goal of the present …

Recent advances on transdermal delivery systems for the treatment of arthritic injuries: From classical treatment to nanomedicines

H Shang, A Younas, N Zhang - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Arthritic injuries happen frequently during a lifetime due to accidents, sports, aging,
diseases, etc. Such injuries can be cartilage/bone injuries, tendon injuries, ligament injuries …

[HTML][HTML] Thermosensitive smart hydrogel of PEITC ameliorates the therapeutic efficacy in rheumatoid arthritis

P Haloi, S Chawla, VB Konkimalla - European Journal of Pharmaceutical …, 2023 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune condition that accompanies chronic
inflammation of joints with limited therapeutic options. Phenethyl isothiocyanate (PEITC), a …

Factorial design based curcumin ethosomal nanocarriers for the skin cancer delivery: in vitro evaluation

MR Peram, S Jalalpure, V Kumbar, S Patil… - Journal of liposome …, 2019 - Taylor & Francis
Melanoma is the most deadly and life-threatening form of skin cancer with progressively
higher rates of incidence worldwide. The objective of the present investigation is to develop …