Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …

Background The amyloid β-protein (Aβ) is believed to be the key mediator of Alzheimer's
disease (AD) pathology. Aβ is most often characterized as an incidental catabolic byproduct …

Alarmins are endogenous molecules that are constitutively available and released upon
tissue damage and activate the immune system. Current evidence indicates that …

Human hair follicles (HFs) carry complex microbial communities that differ from the skin
surface microbiota. This likely reflects that the HF epithelium differs from the epidermal …

Antimicrobial peptides (AMPs) play a critical role in innate host defense against microbial
pathogens in many organisms. The human cathelicidin, LL-37, has a net positive charge …

Host defence peptides (HDPs) are short cationic molecules produced by the immune
systems of most multicellular organisms and play a central role as effector molecules of …

Bone marrow-derived mesenchymal stem cells or multipotent mesenchymal stromal cells
(MSCs) have been shown to engraft into the stroma of several tumor types, where they …

Tumor progression is a multistep phenomenon in which tumor-associated stromal cells
perform an intricate cross-talk with tumor cells, supplying appropriate signals that may …

The antimicrobial peptide LL-37 is the only known member of the cathelicidin family of
peptides expressed in humans. LL-37 is a multifunctional host defense molecule essential …