Horizontal gene transfer among host-associated microbes

JM de Sousa, M Lourenço, I Gordo - Cell Host & Microbe, 2023 - cell.com
Horizontal gene transfer is an important evolutionary force, facilitating bacterial diversity. It is
thought to be pervasive in host-associated microbiomes, where bacterial densities are high …

Intended and unintended consequences of genetically modified crops–myth, fact and/or manageable outcomes?

JR Caradus - New Zealand Journal of Agricultural Research, 2023 - Taylor & Francis
Food and feed has been produced from genetically modified (GM) crops for 25 years. It is
timely to review whether this technology has globally delivered the expected benefits and …

Intra-and interpopulation transposition of mobile genetic elements driven by antibiotic selection

Y Yao, R Maddamsetti, A Weiss, Y Ha… - Nature Ecology & …, 2022 - nature.com
The spread of genes encoding antibiotic resistance is often mediated by horizontal gene
transfer (HGT). Many of these genes are associated with transposons, a type of mobile …

[HTML][HTML] Current methods for recombination detection in bacteria

AE Shikov, YV Malovichko, AA Nizhnikov… - International Journal of …, 2022 - mdpi.com
The role of genetic exchanges, ie, homologous recombination (HR) and horizontal gene
transfer (HGT), in bacteria cannot be overestimated for it is a pivotal mechanism leading to …

HGTphyloDetect: facilitating the identification and phylogenetic analysis of horizontal gene transfer

L Yuan, H Lu, F Li, J Nielsen… - Briefings in …, 2023 - academic.oup.com
Background Horizontal gene transfer (HGT) is an important driver in genome evolution, gain-
of-function, and metabolic adaptation to environmental niches. Genome-wide identification …

Evolutionary mechanisms that determine which bacterial genes are carried on plasmids

S Lehtinen, JS Huisman, S Bonhoeffer - Evolution Letters, 2021 - academic.oup.com
The evolutionary pressures that determine the location (chromosomal or plasmid-borne) of
bacterial genes are not fully understood. We investigate these pressures through …

[HTML][HTML] Bacterial evolution during human infection: adapt and live or adapt and die

MJ Culyba, D Van Tyne - PLoS Pathogens, 2021 - journals.plos.org
Microbes are constantly evolving. Laboratory studies of bacterial evolution increase our
understanding of evolutionary dynamics, identify adaptive changes, and answer important …

The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci

JC D'Aeth, MPG van der Linden, L McGee… - Elife, 2021 - elifesciences.org
Multidrug-resistant Streptococcus pneumoniae emerge through the modification of core
genome loci by interspecies homologous recombinations, and acquisition of gene cassettes …

Computational model to quantify the growth of antibiotic-resistant bacteria in wastewater

I Sutradhar, C Ching, D Desai, M Suprenant, E Briars… - Msystems, 2021 - Am Soc Microbiol
Although wastewater and sewage systems are known to be significant reservoirs of
antibiotic-resistant bacterial populations and periodic outbreaks of drug-resistant infection …

[HTML][HTML] Activation of autophagy through the NLRP3/mTOR pathway: A potential mechanism for alleviation of pneumonia by QingFei yin

X Sun, D Wang, L Ding, Y Xu, W Qi, D Zhao… - Frontiers in …, 2022 - frontiersin.org
QingFei Yin (QFY), a Chinese traditional medicine recipe, is known for its excellent
therapeutic pharmacological effects for the treatment of bacterial lung infections, although its …