[HTML][HTML] Macrophage metabolism in nonalcoholic fatty liver disease
W Zhang, R Lang - Frontiers in Immunology, 2023 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) and its inflammatory and often progressive subtype
nonalcoholic steatohepatitis (NASH), have emerged as significant contributors to hepatic …
nonalcoholic steatohepatitis (NASH), have emerged as significant contributors to hepatic …
Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease
N Fujiwara, N Kubota, E Crouchet, B Koneru… - Science translational …, 2022 - science.org
Prediction of hepatocellular carcinoma (HCC) risk is an urgent unmet need in patients with
nonalcoholic fatty liver disease (NAFLD). In cohorts of 409 patients with NAFLD from …
nonalcoholic fatty liver disease (NAFLD). In cohorts of 409 patients with NAFLD from …
Clinico‐histological and molecular features of hepatocellular carcinoma from nonalcoholic fatty liver disease
N Fujiwara, H Nakagawa - Cancer Science, 2023 - Wiley Online Library
Patients with nonalcoholic fatty liver disease (NAFLD) continue to increase with the
epidemics of obesity, and NAFLD is estimated to become the most prevalent etiology of …
epidemics of obesity, and NAFLD is estimated to become the most prevalent etiology of …
Hepatic fibrosis: targeting peroxisome proliferator-activated receptor alpha from mechanism to medicines
L Gong, F Wei, FJ Gonzalez, G Li - Hepatology, 2023 - journals.lww.com
Liver fibrosis is the result of sustained chronic liver injury and inflammation leading to
hepatocyte cell death followed by the formation of fibrous scars, which is the hallmark of …
hepatocyte cell death followed by the formation of fibrous scars, which is the hallmark of …
[HTML][HTML] Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases
M Thiele, IF Villesen, L Niu, S Johansen, K Sulek… - Journal of …, 2024 - Elsevier
The rising prevalence of liver diseases related to obesity and excessive use of alcohol is
fuelling an increasing demand for accurate biomarkers aimed at community screening …
fuelling an increasing demand for accurate biomarkers aimed at community screening …
Serum α-SMA is a potential noninvasive biomarker of liver fibrosis
I Cardoso-Lezama, E Ramos-Tovar… - Toxicology …, 2024 - Taylor & Francis
The severity of fibrosis is central to the therapeutic course for patients with chronic liver
disease; therefore, early detection of liver fibrosis is critical for timely therapeutic …
disease; therefore, early detection of liver fibrosis is critical for timely therapeutic …
A revisit of drugs and potential therapeutic targets against non-alcoholic fatty liver disease: learning from clinical trials
S Zhu, Z Wu, W Wang, L Wei, H Zhou - Journal of Endocrinological …, 2024 - Springer
Purpose Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease, with a
worldwide prevalence of 25%. Although numerous clinical trials have been conducted over …
worldwide prevalence of 25%. Although numerous clinical trials have been conducted over …
Hepatocellular carcinoma chemoprevention with generic agents
F Rasha, S Paul, TG Simon… - Seminars in liver …, 2022 - thieme-connect.com
Liver cancer, mainly hepatocellular carcinoma (HCC), remains a major cause of cancer-
related death worldwide. With the global epidemic of obesity, the major HCC etiologies have …
related death worldwide. With the global epidemic of obesity, the major HCC etiologies have …
[HTML][HTML] A data-driven approach to decode metabolic dysfunction-associated steatotic liver disease
MJ Ramos, TJ Kendall, I Drozdov, JA Fallowfield - Annals of Hepatology, 2024 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD), defined by the presence
of liver steatosis together with at least one out of five cardiometabolic factors, is the most …
of liver steatosis together with at least one out of five cardiometabolic factors, is the most …
Emerging Roles of Spatial Transcriptomics in Liver Research
N Fujiwara, G Kimura… - Seminars in Liver Disease, 2024 - thieme-connect.com
Spatial transcriptomics, leveraging sequencing-and imaging-based techniques, has
emerged as a groundbreaking technology for mapping gene expression within the complex …
emerged as a groundbreaking technology for mapping gene expression within the complex …