Triglyceride molecules represent the major form of storage and transport of fatty acids within
cells and in the plasma. The liver is the central organ for fatty acid metabolism. Fatty acids …

AMP-activated protein kinase (AMPK) is a metabolic sensor in mammals that is activated
when ATP levels in the cell decrease. AMPK is a heterotrimeric protein that comprises 3 …

The function and survival of all organisms is dependent on the dynamic control of energy
metabolism, when energy demand is matched to energy supply. The AMP-activated protein …

Triacylglycerol (TAG) synthesis and storage in tissues such as adipose tissue and liver have
important roles in metabolic homeostasis. The molecular identification of genes encoding …

Triacylglycerol (TAG) is the primary unit of energy storage in eukaryotic cells. TAG comprises
more than 90% of the content of white adipocytes, and TAG synthesis is essential in …

Peroxisome proliferator-activated receptor γ (PPARγ) is induced in leptin-deficient (ob/ob)
mouse liver and is critical for the development of hepatic steatosis. The present study shows …

Maintenance of body temperature is achieved partly by modulating lipolysis by a network of
complex regulatory mechanisms. Lipolysis is an integral part of the glycerolipid/free fatty …

Obstructive sleep apnea, a syndrome leading to recurrent intermittent hypoxia (IH), has been
associated previously with hypercholesterolemia, independent of underlying obesity. We …

The association of hepatic steatosis with hepatic insulin resistance and type 2 diabetes has
prompted investigators to elucidate the underlying mechanism. In this review we focus on …

Obstructive sleep apnea (OSA) is characterized by chronic intermittent hypoxia (CIH) and
associated with dysregulation of lipid metabolisms and atherosclerosis. Causal relationships …