Antibodies serve as critical barriers to viral infection. Humoral immunity to a virus is achieved
through the dual role of antibodies in communicating the presence of invading pathogens in …

The unprecedented 2013-2016 West Africa Ebola outbreak accelerated several medical
countermeasures (MCMs) against Ebola virus disease (EVD). Several investigational …

Neutralizing antibody function provides a foundation for the efficacy of vaccines and
therapies,–. Here, using a robust in vitro Ebola virus (EBOV) pseudo-particle infection assay …

Long-term follow up studies from Ebola virus disease (EVD) survivors (EBOV_S) are lacking.
Here, we evaluate immune and gene expression profiles in 35 Guinean EBOV_S from the …

Correlates of protection (CoP) are biological parameters that predict a certain level of
protection against an infectious disease. Well-established correlates of protection facilitate …

Summary Background The 2013–16 Ebola virus disease epidemic in west Africa caused
international alarm due to its rapid and extensive spread resulting in a significant death toll …

To clarify the role of bats in the ecology of Ebola viruses, we assessed the prevalence of
Ebola virus antibodies in a large-scale sample of bats collected during 2015–2017 from …

Background Whether or not individuals with pauci-symptomatic or asymptomatic Ebola virus
infection and unrecognised Ebola virus disease develop clinical sequelae is unknown. We …

The 2013–2016 Ebola virus (EBOV) epidemic in West Africa was unprecedented in case
numbers and fatalities, and sporadic outbreaks continue to arise. Antibodies to the EBOV …

Background Insufficient long-term data are available on antibody kinetics in survivors of
Ebola virus disease (EVD). Likewise, few studies, with very small sample sizes, have …