Context: Although antithyroid drug (ATD)-induced hematopoietic damage is a significant
concern, it has not been comprehensively investigated. Objective: Our objective was to …

Background: Antithyroid drugs have been used for more than 50 years for the management
of hyperthyroidism. Most patients tolerate treatment well but some may develop life …

Objective The authors aimed to investigate the clinical characteristics of antithyroid drug-
induced aplastic anemia cases over the past 30 years. Methods The data of patients with …

Pancytopenia is a rare complication of the thionamide therapy reported secondary to
aplastic anemia, the bone marrow being invariably hypocellular. We present a case of a 16 …

Aplastic anemia is a rare but severe complication of methimazole (MMI) treatment for
Graves' disease. We present a case of a 53-year-old Japanese female who had been …

The major adverse reactions of antithyroid drugs are hematologic; aplastic anemia (AA) is
one of the rarest and most severe complications. Use of recombinant human hemopoietic …

Although drug-induced agranulocytosis is infrequent, it is of concern as the mortality rate
ranges from 6 to 10%. Since the approval of granulocyte colony-stimulating factor (G-CSF) …

The best-known adverse hematologic reaction of methimazole is agranulocytosis. Aplastic
anemia is extremely rare. The prognosis within the entity of aplastic anemias is surprisingly …

A 52‐year‐old Japanese woman was examined because of general malaise, weight loss
and a lump in her left breast. She was diagnosed with cancer of the left breast and Graves …

Drug induced agranulocytosis (DIA) is a potentially lethal disorder characterized by selective
neutropenia. Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been utilized …