Immunosuppressive agents and infectious risk in transplantation: managing the “net state of immunosuppression”
MB Roberts, JA Fishman - Clinical Infectious Diseases, 2021 - academic.oup.com
Successful solid organ transplantation reflects meticulous attention to the details of
immunosuppression, balancing risks for graft rejection against risks for infection. The “net …
immunosuppression, balancing risks for graft rejection against risks for infection. The “net …
Microbial transmission in animal social networks and the social microbiome
Host-associated microbiomes play an increasingly appreciated role in animal metabolism,
immunity and health. The microbes in turn depend on their host for resources and can be …
immunity and health. The microbes in turn depend on their host for resources and can be …
Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation
Organ transplantation is a life-saving treatment for patients with end-stage disease, but
survival rates after transplantation vary considerably. There is now increasing evidence that …
survival rates after transplantation vary considerably. There is now increasing evidence that …
Engineering immunomodulatory biomaterials for type 1 diabetes
CL Stabler, Y Li, JM Stewart… - Nature Reviews Materials, 2019 - nature.com
A cure for type 1 diabetes (T1D) would help millions of people worldwide but remains
elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary …
elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary …
Antibiotic pretreatment alleviates liver transplant damage in mice and humans
K Nakamura, S Kageyama, T Ito… - The Journal of …, 2019 - Am Soc Clin Investig
Although modifications of gut microbiota with antibiotics (Abx) influence mouse skin and
cardiac allografts, its role in orthotopic liver transplantation (OLT) remains unknown. We …
cardiac allografts, its role in orthotopic liver transplantation (OLT) remains unknown. We …
Gut microbial metabolites induce donor-specific tolerance of kidney allografts through induction of T regulatory cells by short-chain fatty acids
H Wu, J Singer, TK Kwan, YW Loh… - Journal of the …, 2020 - journals.lww.com
Background Short-chain fatty acids derived from gut microbial fermentation of dietary fiber
have been shown to suppress autoimmunity through mechanisms that include enhanced …
have been shown to suppress autoimmunity through mechanisms that include enhanced …
Shared and distinctive features of the gut microbiome of C57BL/6 mice from different vendors and production sites, and in response to a new vivarium
LL Long, KL Svenson, AJ Mourino, M Michaud… - Lab animal, 2021 - nature.com
Animal models play a critical role in establishing causal relationships between gut
microbiota and disease. The laboratory mouse is widely used to study the role of microbes in …
microbiota and disease. The laboratory mouse is widely used to study the role of microbes in …
Enterococcus faecium Modulates the Gut Microbiota of Broilers and Enhances Phosphorus Absorption and Utilization
W Wang, H Cai, A Zhang, Z Chen, W Chang, G Liu… - Animals, 2020 - mdpi.com
Simple Summary Bone health is an important factor in broiler production. Among the key
nutrients affecting bone health, phosphorus (P) plays a great role. Enterococcus faecium has …
nutrients affecting bone health, phosphorus (P) plays a great role. Enterococcus faecium has …
The gut microbiome in solid organ transplantation
Despite ground‐breaking advances in allogeneic transplantation, allograft rejection and
immunosuppressant‐specific complications remain a major challenge in transplant …
immunosuppressant‐specific complications remain a major challenge in transplant …