[HTML][HTML] Comprehensive elaboration of glycemic variability in diabetic macrovascular and microvascular complications
B Sun, Z Luo, J Zhou - Cardiovascular Diabetology, 2021 - Springer
Diabetes mellitus is the major risk factor for the development of macrovascular and
microvascular complications. It is increasingly recognized that glycemic variability (GV) …
microvascular complications. It is increasingly recognized that glycemic variability (GV) …
Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link
Y Zhang, N Huang, F Yan, H Jin, S Zhou, J Shi… - Behavioural brain …, 2018 - Elsevier
It is well known that Alzheimer's disease (AD) is closely related to diabetes mellitus (DM),
and AD is also regarded as Type 3 diabetes (T3D). However, the exact link between AD and …
and AD is also regarded as Type 3 diabetes (T3D). However, the exact link between AD and …
[HTML][HTML] Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions
M Bensellam, JC Jonas… - Journal of …, 2018 - joe.bioscientifica.com
Like all the cells of an organism, pancreatic β-cells originate from embryonic stem cells
through a complex cellular process termed differentiation. Differentiation involves the …
through a complex cellular process termed differentiation. Differentiation involves the …
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
SA Bustin - Journal of molecular endocrinology, 2000 - jme.bioscientifica.com
To investigate whether the tumor suppressor gene PTEN affects the activity of the androgen
receptor (AR), we monitored the expression of the apoptotic gene HA-Bax (inserted in an …
receptor (AR), we monitored the expression of the apoptotic gene HA-Bax (inserted in an …
Impact of visit-to-visit glycemic variability on the risks of macrovascular and microvascular events and all-cause mortality in type 2 diabetes: the ADVANCE trial
Y Hirakawa, H Arima, S Zoungas, T Ninomiya… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE There is no consensus on the importance of visit-to-visit glycemic variability in
diabetes. Therefore, we assessed the effects of visit-to-visit variability (VVV) in HbA1c and …
diabetes. Therefore, we assessed the effects of visit-to-visit variability (VVV) in HbA1c and …
[HTML][HTML] Long-term visit-to-visit glycemic variability as predictor of micro-and macrovascular complications in patients with type 2 diabetes: the Rio de Janeiro Type 2 …
CRL Cardoso, NC Leite, CBM Moram… - Cardiovascular …, 2018 - Springer
Background Long-term visit-to-visit glycemic variability is an additional measure of glycemic
control. We aimed to evaluate the prognostic value of several measures of glycemic …
control. We aimed to evaluate the prognostic value of several measures of glycemic …
Oxidative stress and beta-cell dysfunction
G Drews, P Krippeit-Drews, M Düfer - Pflügers Archiv-European Journal of …, 2010 - Springer
Diabetes mellitus type 1 and 2 (T1DM and T2DM) are complex multifactorial diseases. Loss
of beta-cell function caused by reduced secretory capacity and enhanced apoptosis is a key …
of beta-cell function caused by reduced secretory capacity and enhanced apoptosis is a key …
The molecular mechanisms of pancreatic β-cell glucotoxicity: recent findings and future research directions
M Bensellam, DR Laybutt, JC Jonas - Molecular and cellular endocrinology, 2012 - Elsevier
It is well established that regular physiological stimulation by glucose plays a crucial role in
the maintenance of the β-cell differentiated phenotype. In contrast, prolonged or repeated …
the maintenance of the β-cell differentiated phenotype. In contrast, prolonged or repeated …
Visit-to-visit glycemic variability and risks of cardiovascular events and all-cause mortality: the ALLHAT study
JB Echouffo-Tcheugui, S Zhao, G Brock… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE The prognostic value of long-term glycemic variability is incompletely
understood. We evaluated the influence of visit-to-visit variability (VVV) of fasting blood …
understood. We evaluated the influence of visit-to-visit variability (VVV) of fasting blood …
'Glycaemic variability': a new therapeutic challenge in diabetes and the critical care setting
A Ceriello, MA Ihnat - Diabetic Medicine, 2010 - Wiley Online Library
Diabet. Med. 27, 862–867 (2010) Abstract Much attention has been paid recently to the
possibility that oscillating glucose may superimpose on glycated haemoglobin (HbA1c) in …
possibility that oscillating glucose may superimpose on glycated haemoglobin (HbA1c) in …