Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

Organoborons have emerged as versatile building blocks in organic synthesis to achieve
molecular diversity and as carboxylic acid bioisosteres with broad applicability in drug …

The amide bond represents the most fundamental functional group in numerous areas of
chemistry, such as organic synthesis, drug discovery, polymers, and biochemistry. Although …

Transition-metal-catalyzed decarbonylation via carbon–carbon bond cleavage is an
essential synthetic methodology. Given the ubiquity of carbonyl compounds, the selective …

Si–B reagents, namely silylboronic esters and silylboranes, have become increasingly
attractive as versatile reagents to introduce silicon and boron atoms into organic …

In recent years, significant conceptual advances have taken place in the field of amide bond
cross-coupling. Mild and selective functionalization of amides by transition-metal catalysis …

Cross-coupling reactions are among the most powerful C–C and C–X bond forming tools in
organic chemistry. Traditionally, cross-coupling methods rely on the use of aryl halides or …

A ligand-controlled and site-selective nickel catalyzed Suzuki–Miyaura cross-coupling
reaction with aromatic esters and alkyl organoboron reagents as coupling partners was …

Transition metal‐catalyzed decarbonylative coupling reactions have emerged as a powerful
alternative to conventional cross‐coupling protocols due to the advantages associated with …

Ground-state destabilization of the N–C (O) linkage represents a powerful tool to
functionalize the historically inert amide bond. This burgeoning reaction manifold relies on …