Oxidative trifluoromethyl (thiol/selenol) ation of terminal alkynes: An overview

A Hassanpour, MRP Heravi, A Ebadi… - Journal of Fluorine …, 2021 - Elsevier
The development of mild, selective, and practical methods for the introduction of fluorine
atom and fluorine-containing functional groups into organic molecules has received …

Trifluoromethylselenolation reactions using the versatile [Me4N][SeCF3] reagent

HN Wang, JY Dong, J Shi, CP Zhang - Tetrahedron, 2021 - Elsevier
The trifluoromethylseleno group (SeCF 3) possesses unique electrosteric effect and high
lipophilicity and has been verified as a pharmaceutically relevant functionality in modulating …

Visible-light-initiated catalyst-free trifluoromethylselenolation of arylsulfonium salts with [Me 4 N][SeCF 3]

ZY Tian, CP Zhang - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
The redox potential gap between arylsulfonium salts and [Me4N][SeCF3] has been clearly
revealed by CV measurements. Construction of the carbon–selenium bond by overcoming …

Lewis Acid Promoted Vicinal Oxytrifluoromethylselenolation of Alkenes

Y Li, S Zhang, Y Wang, Y Gao, C Chen, Z Yuan - Organic Letters, 2023 - ACS Publications
Herein, we have developed a metal-free, Lewis acid promoted vicinal
oxytrifluoromethylselenolation of alkenes using trifluoromethyl selenoxides as electrophilic …

Photoinduced Trifluoromethylselenolation of Aryl Halides with [Me4N][SeCF3]

F Li, X Han, Z Xu, CP Zhang - Organic Letters, 2023 - ACS Publications
A visible-light-induced metal-free trifluoromethylselenolation of aryl iodides and bromides
with [Me4N][SeCF3] is described. The reaction was conducted at ambient temperature by …

Trifluoromethyl Selenoxides: Electrophilic Reagents for C–H Trifluoromethylselenolation of (Hetero) Arene

Y Li, Y Wang, Z Ye, S Zhang, X Ye, Z Yuan - Organic Letters, 2022 - ACS Publications
The trifluoromethylselenyl group (CF3Se) has become an emerging fluorinated moiety in
synthetic chemistry due to its high Hansch lipophilicity parameter and strong electron …

Palladium-catalyzed C–H trifluoromethylselenolation of arenes with [Me 4 N][SeCF 3] and an oxidant

L Liu, YC Gu, CP Zhang - Chemical Communications, 2022 - pubs.rsc.org
Trifluoromethylselenolation of arenes with [Me4N][SeCF3] in the presence of an oxidant
through Pd-catalyzed C (sp2)–H activation under the assistance of a directing group is …

Direct Trifluoromethylselenolation and Fluoroalkylselenolation of C− H Bonds: Recent Advances in Reagents Development and Reactions

Y Gao, R Xiao, S Zhang, Y Wang… - European Journal of …, 2023 - Wiley Online Library
Due to their high lipophilicity and strong electron‐withdrawing property, more and more
attention has been paid to introducing trifluoromethylseleno and fluoroalkylseleno moieties …

Photoinduced Copper-Promoted Decarboxylative Trifluoromethylselenolation of Aromatic Carboxylic Acids with [Me4N][SeCF3]

L Liu, YC Gu, CP Zhang - The Journal of Organic Chemistry, 2023 - ACS Publications
Visible-light-induced decarboxylative trifluoromethylselenolation of (hetero) aromatic
carboxylic acids with [Me4N][SeCF3], oxidant, and catalysts afforded a variety of (hetero) aryl …

Synthesis and Biological Evaluation of CF3Se‐Substituted α‐Amino Acid Derivatives

ZZ Han, T Dong, XX Ming, F Kuang… - ChemMedChem, 2021 - Wiley Online Library
Several CF3Se‐substituted α‐amino acid derivatives, such as (R)‐2‐amino‐3‐
((trifluoromethyl) selanyl) propanoates (5 a/6 a),(S)‐2‐amino‐4‐((trifluoromethyl) selanyl) …