Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …

Nanotechnology has been widely applied to develop drug delivery systems to improve
therapeutic performance. The effectiveness of these systems is intrinsically related to their …

Objective The purpose of this study was to develop novel carbopol-based miltefosine-
loaded transfersomal gel (HePCTG) for the treatment of cutaneous leishmaniasis (CL) via …

Cutaneous leishmaniasis has been endemic since decades. Millions of cases are reported
worldwide specially in developing and underdeveloped countries. There are 2 major types …

Aim: To fabricate and evaluate curcumin-loaded transfersomes (Cur-TF) for the targeted
delivery and enhanced therapeutic efficacy of curcumin for the treatment of rheumatoid …

Topical delivery is preferable over systemic delivery for cutaneous leishmaniasis, because
of its easy administration, reduced systemic adverse effects and low cost. Nitazoxanide …

The stratum corneum, the most superficial layer of the skin, protects the body against
environmental hazards and presents a highly selective barrier for the passage of drugs and …

Topical drug delivery is preferable route over systemic delivery in case of Cutaneous
leishmaniasis (CL). Among the available agents, amphotericin B (AmB) and pentamidine …

As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and
mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to …

Transdermal hydrogels have the potential to improve therapeutic outcomes via enhancing
bioavailability and reducing toxicity associated with oral delivery. The goal of the present …