The field of polymeric nanoparticles is quickly expanding and playing a pivotal role in a wide
spectrum of areas ranging from electronics, photonics, conducting materials, and sensors to …

The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …

Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Stem cells are primitive cells found in many multicellular organisms. Self-renewal and
differentiation potency are two defining properties of stem cells. Self-renewal is the ability to …

Gene delivery using nonviral approaches has been extensively studied as a basic tool for
intracellular gene transfer and gene therapy. In the past, the primary focus has been on …

Polysaccharides contain different functional groups (such as hydroxyl, amino, carboxylic
acid, aldehydes) that make them ideal for conjugation. They are biodegradable …

Many diseases including cardiovascular disease, diabetes, osteoporosis, and cancers
cannot be treated effectively with current clinical therapy because of a significant reduction …

Nanotechnology is poised to make potentially revolutionary innovations in areas of
biomedical science, such as gene therapy and drug therapy. A recently developed …

Background: Magnetic vehicles are very attractive for delivery of therapeutic agents as they
can be targeted to specific locations in the body through the application of a magnetic field …

Therapeutic application of nucleic acids requires their encapsulation in nanosized carriers
that enable safe and efficient intracellular delivery. Before the desired site of action is …