Microcarriers for upscaling cultured meat production
V Bodiou, P Moutsatsou, MJ Post - Frontiers in nutrition, 2020 - frontiersin.org
Due to the considerable environmental impact and the controversial animal welfare
associated with industrial meat production, combined with the ever-increasing global …
associated with industrial meat production, combined with the ever-increasing global …
Bridging the gap between the science of cultured meat and public perceptions
Background The environmental impact of meat consumption requires immediate action.
Cultured meat—which is emerging through technologies to grow meat ex vivo—has exciting …
Cultured meat—which is emerging through technologies to grow meat ex vivo—has exciting …
Spontaneous immortalization of chicken fibroblasts generates stable, high-yield cell lines for serum-free production of cultured meat
Cellular agriculture could meet growing demand for animal products, but yields are typically
low and regulatory bodies restrict genetic modification for cultured meat production. Here we …
low and regulatory bodies restrict genetic modification for cultured meat production. Here we …
High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling
F Manstein, K Ullmann, C Kropp… - Stem cells …, 2021 - academic.oup.com
To harness the full potential of human pluripotent stem cells (hPSCs) we combined
instrumented stirred tank bioreactor (STBR) technology with the power of in silico process …
instrumented stirred tank bioreactor (STBR) technology with the power of in silico process …
Engineering 3D micro-compartments for highly efficient and scale-independent expansion of human pluripotent stem cells in bioreactors
PJR Cohen, E Luquet, J Pletenka, A Leonard, E Warter… - Biomaterials, 2023 - Elsevier
Human pluripotent stem cells (hPSCs) have emerged as the most promising cellular source
for cell therapies. To overcome the scale-up limitations of classical 2D culture systems …
for cell therapies. To overcome the scale-up limitations of classical 2D culture systems …
Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors
BS Borys, T Dang, T So, L Rohani, T Revay… - Stem Cell Research & …, 2021 - Springer
Background Human induced pluripotent stem cells (hiPSCs) hold enormous promise in
accelerating breakthroughs in understanding human development, drug screening, disease …
accelerating breakthroughs in understanding human development, drug screening, disease …
Continuous WNT control enables advanced hPSC cardiac processing and prognostic surface marker identification in chemically defined suspension culture
C Halloin, K Schwanke, W Löbel, A Franke, M Szepes… - Stem Cell Reports, 2019 - cell.com
Aiming at clinical translation, robust directed differentiation of human pluripotent stem cells
(hPSCs), preferentially in chemically defined conditions, is a key requirement. Here …
(hPSCs), preferentially in chemically defined conditions, is a key requirement. Here …
Suspension culture improves iPSC expansion and pluripotency phenotype
Background Induced pluripotent stem cells (iPSCs) offer potential to revolutionize
regenerative medicine as a renewable source for islets, dopaminergic neurons, retinal cells …
regenerative medicine as a renewable source for islets, dopaminergic neurons, retinal cells …
Cells, materials, and fabrication processes for cardiac tissue engineering
P Montero, M Flandes-Iparraguirre… - … in Bioengineering and …, 2020 - frontiersin.org
Cardiovascular disease is the number one killer worldwide, with myocardial infarction (MI)
responsible for approximately 1 in 6 deaths. The lack of endogenous regenerative capacity …
responsible for approximately 1 in 6 deaths. The lack of endogenous regenerative capacity …
[HTML][HTML] Recent advances in bioreactors for cell-based therapies
M Stephenson, W Grayson - F1000Research, 2018 - ncbi.nlm.nih.gov
Bioreactors have become indispensable tools in the cell-based therapy industry. Various
forms of bioreactors are used to maintain well-controlled microenvironments to regulate cell …
forms of bioreactors are used to maintain well-controlled microenvironments to regulate cell …