Radiotheranostics in oncology: making precision medicine possible
EO Aboagye, TD Barwick… - CA: A Cancer Journal for …, 2023 - Wiley Online Library
A quintessential setting for precision medicine, theranostics refers to a rapidly evolving field
of medicine in which disease is diagnosed followed by treatment of disease‐positive …
of medicine in which disease is diagnosed followed by treatment of disease‐positive …
CXCR4-targeted theranostics in oncology
AK Buck, SE Serfling, T Lindner, H Hänscheid… - European Journal of …, 2022 - Springer
A growing body of literature reports on the upregulation of CXC motif chemokine receptor 4
(CXCR4) in a variety of cancer entities, rendering this receptor as suitable target for …
(CXCR4) in a variety of cancer entities, rendering this receptor as suitable target for …
Imaging of CXC motif chemokine receptor 4 expression in 690 patients with solid or hematologic neoplasms using 68Ga-pentixafor PET
In recent years, molecular imaging addressing the CXC motif chemokine receptor 4
(CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess …
(CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess …
[HTML][HTML] Targeting CXCR4 in AML and all
D Cancilla, MP Rettig, JF DiPersio - Frontiers in oncology, 2020 - frontiersin.org
The interaction of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL)
blasts with the bone marrow microenvironment regulates self-renewal, growth signaling, as …
blasts with the bone marrow microenvironment regulates self-renewal, growth signaling, as …
Clinical advances and perspectives in targeted radionuclide therapy
N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …
In vivo targeting of CXCR4—new horizons
M Schottelius, K Herrmann, C Lapa - Cancers, 2021 - mdpi.com
Simple Summary Beyond its pre-eminent role in the context of tumor cell growth as well as
metastasis, the CXC motif chemokine receptor 4 (CXCR4) is a key player in the …
metastasis, the CXC motif chemokine receptor 4 (CXCR4) is a key player in the …
CXC motif chemokine receptor 4–targeted radioligand therapy in patients with advanced T-cell lymphoma
CXC motif chemokine receptor 4 (CXCR4)–targeted radioligand therapy (RLT) has already
been applied to advanced blood cancers, such as multiple myeloma or diffuse large B-cell …
been applied to advanced blood cancers, such as multiple myeloma or diffuse large B-cell …
[HTML][HTML] CXCR4-directed imaging in solid tumors
Despite histological evidence in various solid tumor entities, available experience with
CXCR4-directed diagnostics and endoradiotherapy mainly focuses on hematologic …
CXCR4-directed diagnostics and endoradiotherapy mainly focuses on hematologic …
CXCR4-targeted PET imaging of central nervous system B-cell lymphoma
P Herhaus, J Lipkova, F Lammer… - Journal of Nuclear …, 2020 - Soc Nuclear Med
CXC chemokine receptor 4 (CXCR4) is a transmembrane chemokine receptor involved in
growth, survival, and dissemination of cancer, including aggressive B-cell lymphoma. MRI is …
growth, survival, and dissemination of cancer, including aggressive B-cell lymphoma. MRI is …
Theranostics in hematooncology
In the early 2000s, major clinical trials provided evidence of a favorable outcome from
antibody-mediated radioimmunotherapy for hematologic neoplasms, which then led to Food …
antibody-mediated radioimmunotherapy for hematologic neoplasms, which then led to Food …