Despite advances in cancer detection and therapy, it has been estimated that the incidence
of cancers will increase, while the mortality rate will continue to remain high, a fact explained …

Introduction Immune-checkpoint inhibitors (ICIs) have emerged as a core pillar of cancer
therapy as single agents or in combination regimens both in adults and children …

Background: Gastric cancer (GC) is a common cancer with high mortality. This study aimed
to identify its differentially expressed genes (DEGs) using bioinformatics methods. Methods …

Glioma is the most common primary brain tumor in the human brain. The present study was
designed to explore the expression of PIMREG in glioma and its relevance to the …

Tubulin alpha-1c chain (TUBA1C), a subtype of α-tubulin, has been shown to be involved in
cell proliferation and cell cycle progression in several cancers and to influence cancer …

Motivation The identification of cancer genes is a critical yet challenging problem in cancer
genomics research. Existing computational methods, including deep graph neural networks …

Background Phosphatidylinositol binding clathrin assembly protein interacting mitotic
regulator (PIMREG) expression is upregulated in a variety of cancers. However, its potential …

Liver hepatocellular carcinoma (LIHC) is a malignancy with a high mortality and morbidity
rate worldwide. However, the pathogenesis of LIHC has still not been thoroughly studied …

Triple-negative breast cancer (TNBC) is an exceptionally aggressive subtype of breast
cancer. Despite the recognized interplay between tumors and tumor-associated …

Hepatocellular carcinoma (HCC) is one of the deadliest malignancies worldwide, with late
detection, ineffective treatment and poor overall survival. Immunotherapy, including immune …