Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Dopamine: functions, signaling, and association with neurological diseases

MO Klein, DS Battagello, AR Cardoso… - Cellular and molecular …, 2019 - Springer
The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …

Modafinil: a review of neurochemical actions and effects on cognition

MJ Minzenberg, CS Carter - Neuropsychopharmacology, 2008 - nature.com
Abstract Modafinil (2-[(Diphenylmethyl) sulfinyl] acetamide, Provigil) is an FDA-approved
medication with wake-promoting properties. Pre-clinical studies of modafinil suggest a …

α1-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition

DM Perez - Frontiers in pharmacology, 2020 - frontiersin.org
α1-adrenergic receptors are G-Protein Coupled Receptors that are involved in
neurotransmission and regulate the sympathetic nervous system through binding and …

Identification of wake-active dopaminergic neurons in the ventral periaqueductal gray matter

J Lu, TC Jhou, CB Saper - Journal of Neuroscience, 2006 - Soc Neuroscience
Recent evidence suggests that dopamine plays an important role in arousal, but the location
of the dopaminergic neurons that may regulate arousal remains unclear. It is sometimes …

The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

M Meyrath, M Szpakowska, J Zeiner, L Massotte… - Nature …, 2020 - nature.com
Endogenous opioid peptides and prescription opioid drugs modulate pain, anxiety and
stress by activating opioid receptors, currently classified into four subtypes. Here we …

Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors

S Pittolo, S Yokoyama, DD Willoughby, CR Taylor… - Cell reports, 2022 - cell.com
The prefrontal cortex (PFC) is a hub for cognitive control, and dopamine profoundly
influences its functions. In other brain regions, astrocytes sense diverse neurotransmitters …

Is brain estradiol a hormone or a neurotransmitter?

J Balthazart, GF Ball - Trends in neurosciences, 2006 - cell.com
Mounting evidence indicates that, besides their well-known hormonal mode of action at the
genetic level, estrogens such as 17β-estradiol also influence brain function by direct effects …

Functional significance of the rapid regulation of brain estrogen action: where do the estrogens come from?

CA Cornil, GF Ball, J Balthazart - Brain research, 2006 - Elsevier
Estrogens exert a wide variety of actions on reproductive and non-reproductive functions.
These effects are mediated by slow and long lasting genomic as well as rapid and transient …

Has dopamine a physiological role in the control of sexual behavior?: a critical review of the evidence

RG Paredes, A Ågmo - Progress in neurobiology, 2004 - Elsevier
The role of dopaminergic systems in the control of sexual behavior has been a subject of
study for at least 40 years. Not surprisingly, reviews of the area have been published at …