Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Cyanine dyes containing quinoline moieties: history, synthesis, optical properties, and applications

K Ilina, M Henary - Chemistry–A European Journal, 2021 - Wiley Online Library
Cyanine dyes carrying quinoline moieties are an important class of organic molecules that
are of great interest for applications in many fields like medicine, pharmacology, and …

Quinolinium-based viscosity probes for lysosome imaging and tracing lysosomal viscosity changes in living cells

A Tantipanjaporn, KKY Kung, WC Chan… - Sensors and Actuators B …, 2022 - Elsevier
Lysosomal viscosity fluctuation is related to various diseases such as diabetes,
neurodegenerative diseases, and cancer. We designed and synthesized four novel pH …

Hantzsch‐Like Synthesis, DNA Photocleavage, DNA/BSA Binding, and Molecular Docking Studies of Bis (sulfanediyl) bis (tetrahydro‐5‐deazaflavin) Analogs Linked …

MA Ragheb, RE Abdelwahab… - Chemistry & …, 2022 - Wiley Online Library
The cyclocondensation reaction of aldehydes with dimedone and bis (6‐aminopyrimidin‐4‐
one) in acetic acid led to the formation of the corresponding bis (pyrimido [4, 5‐b] quinoline …

Donor acceptor fluorophores: synthesis, optical properties, TD-DFT and cytotoxicity studies

ZM Essam, GE Ozmen, D Setiawan… - Organic & …, 2021 - pubs.rsc.org
Donor–π-acceptor (D–π-A) fluorophores consisting of a donor unit, a π linker, and an
acceptor moiety have attracted attention in the last decade. In this study, we report the …

Recent Applications of Quinolinium Salts in the Synthesis of Annulated Heterocycles

S Das - SynOpen, 2022 - thieme-connect.com
Quinoline derivatives are frequently found in natural products and biologically active
compounds; however, construction of quinoline fused polyheterocycles is a challenging goal …

New Insights into the Phototoxicity of Anthracene-Based Chromophores: The Chloride Salt Effect

MS Safiarian, A Ugboya, I Khan… - Chemical Research …, 2023 - ACS Publications
Unraveling the causes underlying polycyclic aromatic hydrocarbon phototoxicity is an
essential step in understanding the harmful effects of these compounds in nature. Toward …

DNA photocleavage in the near-infrared wavelength range by 2-quinolinium dicarbocyanine dyes

EO Ahoulou, KK Drinkard, K Basnet, A St. Lorenz… - Molecules, 2020 - mdpi.com
Here, we report the syntheses of two pentamethine cyanine dyes containing quinolinium
rings and substituted with either hydrogen (3) or bromine (4) at the meso carbon. The …

Synthesis of 2-Amino-N′-aroyl(het)arylhydrazides, DNA Photocleavage, Molecular Docking and Cytotoxicity Studies against Melanoma CarB Cell Lines

A Mitrakas, MEK Stathopoulou, C Mikra… - Molecules, 2024 - mdpi.com
Diacylhydrazine bridged anthranilic acids with aryl and heteroaryl domains have been
synthesized as the open flexible scaffold of arylamide quinazolinones in order to investigate …

Investigation into Novel Mitochondrial Targeting Cyanine Dyes as Potential Photosensitizing Agents for Photodynamic Therapy

D Brewer - 2022 - scholarworks.gsu.edu
Carbocyanine dyes are a class of organic compounds with high conjugation that enable
them to act as photosensitizing agents in photodynamic therapy (PDT). These compounds …