[HTML][HTML] RdRp (RNA-dependent RNA polymerase): A key target providing anti-virals for the management of various viral diseases
With the arrival of the Covid-19 pandemic, anti-viral agents have regained center stage in
the arena of medicine. Out of the various drug targets involved in managing RNA-viral …
the arena of medicine. Out of the various drug targets involved in managing RNA-viral …
Small molecule NS5B RdRp non-nucleoside inhibitors for the treatment of HCV infection: A medicinal chemistry perspective
Z Zhou, J Zhang, E Zhou, C Ren, J Wang… - European Journal of …, 2022 - Elsevier
Hepatitis C virus (HCV) infection has become a global health problem with enormous risks.
Nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp) is a component …
Nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp) is a component …
Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors
AM Srour, NS Ahmed, SS Abd El-Karim… - Bioorganic & Medicinal …, 2020 - Elsevier
Heterocyclic rings such as thiazole and benzimidazole are considered as privileged
structures, since they constitute several FDA-approved drugs for cancer treatment. In this …
structures, since they constitute several FDA-approved drugs for cancer treatment. In this …
Potential Fluorinated Anti‐MRSA Thiazolidinone Derivatives with Antibacterial, Antitubercular Activity and Molecular Docking Studies
V Kumar, P Shetty, A HS, S Chandra K… - Chemistry & …, 2022 - Wiley Online Library
MRSA infection is one of the alarming diseases in the current scenario. Identifying newer
molecules to treat MRSA infection is of urgent need. In the present study, we have designed …
molecules to treat MRSA infection is of urgent need. In the present study, we have designed …
Design, synthesis, and anticancer activity of novel 4-thiazolidinone-phenylaminopyrimidine hybrids
Thiazolidinones and phenylaminopyrimidines are known as anticancer agents. Imatinib is
the pioneer phenylaminopyrimidine derivative kinase inhibitor, which is used for the …
the pioneer phenylaminopyrimidine derivative kinase inhibitor, which is used for the …
Facile synthesis of 1, 3-thiazolidin-4-ones as antitubercular agents
We have developed, highly efficient, one-pot, solvent-free,[Et 3 NH][HSO 4] catalyzed
multicomponent reaction protocol for the synthesis of 1, 3-thiazolidin-4-ones in excellent …
multicomponent reaction protocol for the synthesis of 1, 3-thiazolidin-4-ones in excellent …
Sonochemical Green Synthesis of Yttrium Oxide (Y2O3) Nanoparticles as a Novel Heterogeneous Catalyst for the Construction of Biologically Interesting 1,3 …
This paper describes a facile and green strategy for the synthesis of yttrium oxide
nanoparticles (Y 2 O 3 NPs) by a straightforward process using Liriope platyphylla rhizome …
nanoparticles (Y 2 O 3 NPs) by a straightforward process using Liriope platyphylla rhizome …
Design, synthesis, and biological evaluation of imidazopyridine‐linked thiazolidinone as potential anticancer agents
In this study, two series of imidazopyridine‐linked thiazolidinone rings (5a–h and 6a–h)
constituting 16 new compounds were synthesized and tested for their antiproliferative …
constituting 16 new compounds were synthesized and tested for their antiproliferative …
[HTML][HTML] Design, synthesis, and molecular docking studies of a conjugated thiadiazole–thiourea scaffold as antituberculosis agents
Design, Synthesis, and Molecular Docking Studies of a Conjugated Thiadiazole–Thiourea
Scaffold as Antituberculosis Agents Toggle navigation J-STAGE home Browse All titles All …
Scaffold as Antituberculosis Agents Toggle navigation J-STAGE home Browse All titles All …
Synthesis and evaluation of novel 1, 3, 4-thiadiazole--fluoroquinolone hybrids as antibacterial, antituberculosis, and anticancer agents
A Demirci, KG KARAYEL, E Tatar… - Turkish Journal of …, 2018 - journals.tubitak.gov.tr
Abstract A series of 5-substituted-1, 3, 4-thiadiazole-based fluoroquinolone derivatives were
designed as potential antibacterial and anticancer agents using a molecular hybridization …
designed as potential antibacterial and anticancer agents using a molecular hybridization …