Conditioned place preference (CPP) continues to be one of the most popular models to
study the motivational effects of drugs and non‐drug treatments in experimental animals …

Some psychoactive drugs are abused because of their ability to act as reinforcers. As a
consequence behavioural patterns (such as drug‐seeking/drug‐taking behaviours) are …

Little is known about the genetic changes that distinguish domestic cat populations from
their wild progenitors. Here we describe a high-quality domestic cat reference genome …

The nucleus accumbens (NAc) is a critical element of the mesocorticolimbic system, a brain
circuit implicated in reward and motivation. This basal forebrain structure receives dopamine …

The past two decades have witnessed a dramatic accumulation of evidence indicating that
the excitatory amino acid glutamate plays an important role in drug addiction and …

The main characteristics of cocaine addiction are compulsive drug use despite adverse
consequences and high rates of relapse during periods of abstinence. A current popular …

Addictive drugs hijack mechanisms of learning and memory that normally underlie
reinforcement of natural rewards and induce synaptic plasticity of glutamatergic transmission …

This review focuses on cocaine-induced postsynaptic plasticity in the nucleus accumbens
(NAc) involving changes in AMPA receptor (AMPAR) transmission. First, fundamental …

Cocaine strengthens excitatory synapses onto midbrain dopamine neurons through the
synaptic delivery of GluR1-containing AMPA receptors. This cocaine-evoked plasticity …

Simple Summary The domestic cat is the only species within the felis genus to have
transitioned from a wild, solitary species to one of the most popular human-companion …