Polymer-based nanomaterials and applications for vaccines and drugs

J Han, D Zhao, D Li, X Wang, Z Jin, K Zhao - Polymers, 2018 - mdpi.com
Nanotechnology plays a significant role in drug development. As carriers, polymeric
nanoparticles can deliver vaccine antigens, proteins, and drugs to the desired site of action …

The influence of component structural arrangement on peptide vaccine immunogenicity

N Alharbi, M Skwarczynski, I Toth - Biotechnology Advances, 2022 - Elsevier
Peptide-based subunit vaccines utilise minimal immunogenic components (ie peptides) to
generate highly specific immune responses, without triggering adverse reactions. However …

Applications of polymer-based nanoparticles in vaccine field

S Guo, D Fu, A Utupova, D Sun, M Zhou… - Nanotechnology …, 2019 - degruyter.com
Polymer-based nanoparticles have good solubility, stability, safety, and sustained release,
which increases the absorption of loaded drugs, protects the drugs from degradation, and …

Development of effective tumor vaccine strategies based on immune response cascade reactions

H Wu, X Fu, Y Zhai, S Gao, X Yang… - Advanced Healthcare …, 2021 - Wiley Online Library
To solve the problems of high toxicity and poor efficacy of existing tumor treatment methods,
researchers have developed a variety of tumor immunotherapies. Among them, tumor …

Polymeric hydrogel based systems for vaccine delivery: A review

P Basu, N Saha, T Saha, P Saha - Polymer, 2021 - Elsevier
The appropriate delivery of vaccines is a significant factor for the proper immunization. The
proper delivery of the cargo vaccine/antigen along with stimulation of high antigen mediated …

Defined small molecules produced by Himalayan medicinal plants display immunomodulatory properties

P Wangchuk, SH Apte, MJ Smout, PL Groves… - International journal of …, 2018 - mdpi.com
Plant-derived compounds that modulate the immune responses are emerging as frontline
treatment agents for cancer, infectious diseases and autoimmunity. Herein we have isolated …

Quaternized chitosan nanoparticles in vaccine applications

S Yu, S Hao, B Sun, D Zhao, X Yan… - Current Medicinal …, 2020 - ingentaconnect.com
Different natural and synthetic biodegradable polymers have been used in vaccine
formulations as adjuvant and delivery system but have faced various limitations. Chitosan is …

Natural Polymeric Composites Derived from Animals, Plants, and Microbes for Vaccine Delivery and Adjuvant Applications: A Review

AH Nordin, SMN Husna, Z Ahmad, ML Nordin, RA Ilyas… - Gels, 2023 - mdpi.com
A key element in ensuring successful immunization is the efficient delivery of vaccines.
However, poor immunogenicity and adverse inflammatory immunogenic reactions make the …

Polymeric beads for targeted drug delivery and healthcare applications

V Khwaza, B Buyana, X Nqoro, R Ngonidzashe… - Polymeric Biomaterials …, 2022 - Elsevier
Many currently available conventional drugs suffer from problems of drug resistance, drug
toxicity, poor water solubility, and severe side effects. To overcome these limitations, several …

Biodegradable Polymers in Vaccine Delivery

M Kenchegowda, S Guruswamy… - Handbook of …, 2025 - taylorfrancis.com
Vaccination has a major impact on the control of infectious diseases and is the most cost-
effective method to prevent disease. Novel vaccines offer longer durability and improved …