The efficacy of COVID-19 vaccines in chronic kidney disease and kidney transplantation patients: a narrative review
YC Hou, KC Lu, KL Kuo - Vaccines, 2021 - mdpi.com
The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic has posed a
huge threat to global health because of its rapid spread and various mutant variants. Critical …
huge threat to global health because of its rapid spread and various mutant variants. Critical …
Does oxidative stress management help alleviation of COVID-19 symptoms in patients experiencing diabetes?
Severe acute respiratory syndrome (SARS)-CoV-2 virus causes novel coronavirus disease
2019 (COVID-19) with other comorbidities such as diabetes. Diabetes is the most common …
2019 (COVID-19) with other comorbidities such as diabetes. Diabetes is the most common …
[HTML][HTML] A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
It is not well understood why diabetic individuals are more prone to develop severe COVID-
19. To this, we here established a human kidney organoid model promoting early hallmarks …
19. To this, we here established a human kidney organoid model promoting early hallmarks …
Urinary single-cell profiling captures the cellular diversity of the kidney
Urinary Single-Cell Profiling Captures the Cellular Diversit... : Journal of the American Society
of Nephrology Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney …
of Nephrology Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney …
[HTML][HTML] Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations
Kidneys are critical target organs of COVID-19, but susceptibility and responses to infection
remain poorly understood. Here, we combine SARS-CoV-2 variants with genome-edited …
remain poorly understood. Here, we combine SARS-CoV-2 variants with genome-edited …
[HTML][HTML] Urinary EGF and MCP-1 and risk of CKD after cardiac surgery
S Menez, W Ju, R Menon, DG Moledina, HT Philbrook… - Jci Insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Assessment of chronic kidney disease (CKD) risk after acute kidney injury
(AKI) is based on limited markers primarily reflecting glomerular function. We evaluated …
(AKI) is based on limited markers primarily reflecting glomerular function. We evaluated …
ACE2 protein expression within isogenic cell lines is heterogeneous and associated with distinct transcriptomes
EJ Sherman, BT Emmer - Scientific reports, 2021 - nature.com
The membrane protein angiotensin-converting enzyme 2 (ACE2) is a physiologic regulator
of the renin-angiotensin system and the cellular receptor for the SARS-CoV-2 virus. Prior …
of the renin-angiotensin system and the cellular receptor for the SARS-CoV-2 virus. Prior …
[HTML][HTML] Molecular programs associated with glomerular hyperfiltration in early diabetic kidney disease
Hyperfiltration is a state of high glomerular filtration rate (GFR) observed in early diabetes
that damages glomeruli, resulting in an iterative process of increasing filtration load on fewer …
that damages glomeruli, resulting in an iterative process of increasing filtration load on fewer …
Urinary proteomics identifies cathepsin D as a biomarker of rapid eGFR decline in type 1 diabetes
OBJECTIVE Understanding mechanisms underlying rapid estimated glomerular filtration
rate (eGFR) decline is important to predict and treat kidney disease in type 1 diabetes (T1D) …
rate (eGFR) decline is important to predict and treat kidney disease in type 1 diabetes (T1D) …
Sodium-glucose co-transporter 2 inhibitors in COVID-19: Meeting at the crossroads between heart, diabetes and infectious diseases
T Koufakis, AN Pavlidis, S Metallidis… - International Journal of …, 2021 - Springer
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are a new class of glucose-lowering
agents which have changed the landscape of diabetes therapy, due to their remarkable …
agents which have changed the landscape of diabetes therapy, due to their remarkable …