Oxidative stress in radiation‐induced cardiotoxicity

Z Ping, Y Peng, H Lang, C Xinyong… - Oxidative medicine …, 2020 - Wiley Online Library
There is a distinct increase in the risk of heart disease in people exposed to ionizing
radiation (IR). Radiation‐induced heart disease (RIHD) is one of the adverse side effects …

Nanodrugs with intrinsic radioprotective exertion: Turning the double‐edged sword into a single‐edged knife

J Guo, Z Zhao, ZF Shang, Z Tang, H Zhu, K Zhang - Exploration, 2023 - Wiley Online Library
Ionizing radiation (IR) poses a growing threat to human health, and thus ideal
radioprotectors with high efficacy and low toxicity still receive widespread attention in …

Early to sustained impacts of lethal radiation on circulating miRNAs in a minipig model

N Chakraborty, GP Holmes-Hampton, A Gautam… - Scientific Reports, 2023 - nature.com
Early diagnosis of lethal radiation is imperative since its intervention time windows are
considerably short. Hence, ideal diagnostic candidates of radiation should be easily …

Protection of the hematopoietic system against radiation-induced damage: drugs, mechanisms, and developments

Y Wei, Y Gong, S Wei, Y Chen, J Cui, X Lin… - Archives of Pharmacal …, 2022 - Springer
Sometimes, people can be exposed to moderate or high doses of radiation accidentally or
through the environment. Radiation can cause great harm to several systems within …

Gene expression profiles from heart, lung and liver samples of total-body-irradiated minipigs: Implications for predicting radiation-induced tissue toxicity

S Chopra, M Moroni, S Martello, M Bylicky… - Radiation …, 2020 - meridian.allenpress.com
In the event of a major accidental or intentional radiation exposure incident, the affected
population could suffer from total-or partial-body exposures to ionizing radiation with acute …

[HTML][HTML] Medical countermeasures for the hematopoietic-subsyndrome of acute radiation syndrome in space

DN Kernagis, E Balcer-Kubiczek, S Bazyar… - Life sciences in space …, 2022 - Elsevier
More than 50 years after the Apollo missions ended, the National Aeronautical and Space
Administration (NASA) and other international space agencies are preparing a return to the …

Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome

WB Rittase, EA McCart, JM Muir, RM Bouten… - Plos one, 2021 - journals.plos.org
Our laboratory has demonstrated that captopril, an angiotensin converting enzyme inhibitor,
mitigates hematopoietic injury following total body irradiation in mice. Improved survival in …

Acute and late effects of combined internal and external radiation exposures on the hematopoietic system

LM Calvi, BJ Frisch, PD Kingsley… - … Journal of Radiation …, 2019 - Taylor & Francis
Purpose: Incidents, such as nuclear facility accidents and the release of a 'dirty bomb', might
result in not only external irradiation of personnel, but additional internal exposures through …

Late health effects of partial body irradiation injury in a minipig model are associated with changes in systemic and cardiac IGF-1 signaling

B Hritzo, SY Aghdam, B Legesse, A Kaur… - International Journal of …, 2021 - mdpi.com
Clinical, epidemiological, and experimental evidence demonstrate non-cancer,
cardiovascular, and endocrine effects of ionizing radiation exposure including growth …

Delayed renal injury in survivors of hematologic acute radiation syndrome

T Gasperetti, A Frei, G Prasad Sharma… - … journal of radiation …, 2023 - Taylor & Francis
Purpose A mass casualty disaster involving radiological or nuclear agents continues to be a
public health concern which requires consideration of both acute and late tissue toxicities in …