[HTML][HTML] Discovery and development of safe-in-man broad-spectrum antiviral agents
PI Andersen, A Ianevski, H Lysvand… - International Journal of …, 2020 - Elsevier
Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-
specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases …
specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases …
Coronavirus COVID-19: Available free literature provided by various companies, journals and organizations around the world
S Nadeem - Journal of Ongoing Chemical Research, 2020 - dergipark.org.tr
Human history is observing a very strange time fighting an invisible enemy; the novel COVID-
19 coronavirus. Initially observed in the Wuhan province of China, now fastly spreading …
19 coronavirus. Initially observed in the Wuhan province of China, now fastly spreading …
Preparing for the next viral threat with broad-spectrum antivirals
There is a large global unmet need for the development of countermeasures to combat
hundreds of viruses known to cause human disease and for the establishment of a …
hundreds of viruses known to cause human disease and for the establishment of a …
Doxycycline-encapsulated solid lipid nanoparticles as promising tool against Brucella melitensis enclosed in macrophage: a pharmacodynamics study on J774A.1 …
SM Hosseini, R Abbasalipourkabir, FA Jalilian… - … Resistance & Infection …, 2019 - Springer
Background Brucellosis is a zoonotic disease caused by Brucella species. It has been
estimated that more than 500,000 new cases of Brucellosis occur annually all around the …
estimated that more than 500,000 new cases of Brucellosis occur annually all around the …
Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …
propagate and cause fatal diseases. The microbes overpower host immunity at various …
[HTML][HTML] Pomegranate peel induced biogenic synthesis of silver nanoparticles and their multifaceted potential against intracellular pathogen and cancer
In the field of nano-biotechnology, silver nanoparticles (AgNPs) share a status of high repute
owing to their remarkable medicinal values. Biological synthesis of environment-friendly …
owing to their remarkable medicinal values. Biological synthesis of environment-friendly …
Metformin and Covid-19: focused review of mechanisms and current literature suggesting benefit
S Ibrahim, JR Lowe, CT Bramante, S Shah… - Frontiers in …, 2021 - frontiersin.org
Metformin is the first-line medication for type 2 diabetes, but it also has a long history of
improved outcomes in infectious diseases, such as influenza, hepatitis C, and in-vitro assays …
improved outcomes in infectious diseases, such as influenza, hepatitis C, and in-vitro assays …
Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment
There is an urgent need for strategies to combat dengue virus (DENV) infection; a major
global threat. We reported that the cellular kinases AAK1 and GAK regulate intracellular …
global threat. We reported that the cellular kinases AAK1 and GAK regulate intracellular …
Induction of Programmed Cell Death in Acanthamoeba culbertsoni by the Repurposed Compound Nitroxoline
RL Rodríguez-Expósito, I Sifaoui, M Reyes-Batlle… - Antioxidants, 2023 - mdpi.com
Acanthamoeba is a ubiquitous genus of amoebae that can act as opportunistic parasites in
both humans and animals, causing a variety of ocular, nervous and dermal pathologies …
both humans and animals, causing a variety of ocular, nervous and dermal pathologies …
Analysis of erythrocyte signalling pathways during Plasmodium falciparum infection identifies targets for host-directed antimalarial intervention
JD Adderley, S John von Freyend, SA Jackson… - Nature …, 2020 - nature.com
Intracellular pathogens mobilize host signaling pathways of their host cell to promote their
own survival. Evidence is emerging that signal transduction elements are activated in a …
own survival. Evidence is emerging that signal transduction elements are activated in a …