Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and
function and constitute risk factors for cognitive impairment. Alterations to taurine …

Glycine is a primary inhibitory neurotransmitter in the spinal cord and brainstem. It acts at
glycine receptor (GlyR)-chloride channels, as well as a co-agonist of NMDA receptors …

Background: With the advent of genome-wide analyses, it is becoming evident that a large
number of noncoding RNAs (ncRNAs) are expressed in vertebrates. However, of the …

Results: It was found that ammonia inhibited mitochondrial dehydrogenases activity caused
collapse of mitochondrial membrane potential (MMP), induced mitochondrial swelling …

Taurine is one of the most abundant free amino acids in the brain. In a number of studies,
taurine has been reported to activate glycine receptors (Gly-Rs) at moderate concentrations …

Neurotransmitter receptors are central to communication at synapses. Many components of
the machinery for neurotransmission are present prior to synapse formation, suggesting a …

Ethanol (EtOH) is a drug widely consumed throughout the world that promotes several
neurochemical disorders. Its deleterious effects are generally associated with modifications …

Functional glycine receptors (GlyRs) are enriched in the hippocampus, but their role in
hippocampal function remains unclear. Since the concentration of ambient glycine is …

Temporal specification of the neural progenitors (NPs) producing excitatory glutamatergic
neurons is essential for histogenesis of the cerebral cortex. Neuroepithelial cells, the primary …

This article briefly describes the trophic actions of taurine in the developing brain,
contribution of taurine to the volume regulation of brain cells, and the interference of taurine …