A majority of patients with Alzheimer's disease (AD) experience some form of sleep
disruption, including nocturnal sleep fragmentation, increased daytime napping, decreased …

Simple Summary Electrical activity in the brain dynamically changes throughout the day.
Abnormalities in brain activity have been associated with various brain disorders, including …

No prior studies have evaluated the efficacy and safety of zolpidem and zopiclone to treat
insomnia of demented patients. This randomized, triple-blind, placebo-controlled clinical trial …

Background: Benzodiazepines (BZDs) and Non-BZDs (NBZDs) have been widely used for
patients with chronic insomnia. Long-term uses of BZDs may cause cognitive impairment …

Objective Mild cognitive impairment (MCI) is associated with increased memory problems
although the ability to complete daily life activities remains relatively intact. This study …

Alzheimer's disease (AD) is associated with a very large burden on global healthcare
systems. Thus, it is imperative to find effective treatments of the disease. One feature of AD is …

Many risk factors for dementia, identified from observational studies, are potentially
modifiable. This raises the possibility that targeting key modifiable dementia risk factors may …

Purpose This study sought to describe patient characteristics and treatment patterns among
patients with insomnia prescribed trazodone in the United States. Methods This real-world …

We have an increasingly aging population and, therefore, cognitive impairment and
dementia are becoming more common. Similarly, sleep disorders are also more common …

Background: The association between sleep and Alzheimer's disease (AD) biomarkers are
well-established, but little is known about how they interact to change the course of AD …