Vestibular involvement in cognition: Visuospatial ability, attention, executive function, and memory

RT Bigelow, Y Agrawal - Journal of vestibular research, 2015 - content.iospress.com
A growing body of literature suggests the inner ear vestibular system has a substantial
impact on cognitive function. The strongest evidence exists in connecting vestibular function …

A review of alterations to the brain during spaceflight and the potential relevance to crew in long-duration space exploration

M Roy-O'Reilly, A Mulavara, T Williams - npj Microgravity, 2021 - nature.com
During spaceflight, the central nervous system (CNS) is exposed to a complex array of
environmental stressors. However, the effects of long-duration spaceflight on the CNS and …

Neuro-consequences of the spaceflight environment

SD Mhatre, J Iyer, S Puukila, AM Paul… - Neuroscience & …, 2022 - Elsevier
As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Head-down tilt bed rest studies as a terrestrial analog for spaceflight associated neuro-ocular syndrome

J Ong, AG Lee, HE Moss - Frontiers in Neurology, 2021 - frontiersin.org
Astronauts who undergo prolonged periods of spaceflight may develop a unique
constellation of neuro-ocular findings termed Spaceflight Associated Neuro-Ocular …

[HTML][HTML] Effects of isolation and confinement on humans-implications for manned space explorations

JI Pagel, A Choukèr - Journal of Applied Physiology, 2016 - journals.physiology.org
Human psychology and physiology are significantly altered by isolation and confinement. In
light of planned exploration class interplanetary missions, the related adverse effects on the …

Longitudinal MRI-visible perivascular space (PVS) changes with long-duration spaceflight

KE Hupfeld, SB Richmond, HR McGregor… - Scientific reports, 2022 - nature.com
Humans are exposed to extreme environmental stressors during spaceflight and return with
alterations in brain structure and shifts in intracranial fluids. To date, no studies have …

Brain structural plasticity with spaceflight

V Koppelmans, JJ Bloomberg, AP Mulavara… - npj …, 2016 - nature.com
Humans undergo extensive sensorimotor adaptation during spaceflight due to altered
vestibular inputs and body unloading. No studies have yet evaluated the effects of …

Brain and behavioral evidence for reweighting of vestibular inputs with long-duration spaceflight

KE Hupfeld, HR McGregor, V Koppelmans… - Cerebral …, 2022 - academic.oup.com
Microgravity alters vestibular signaling. In-flight adaptation to altered vestibular afferents is
reflected in post-spaceflight aftereffects, evidenced by declines in vestibularly mediated …

Alterations of functional brain connectivity after long-duration spaceflight as revealed by fMRI

E Pechenkova, I Nosikova, A Rumshiskaya… - Frontiers in …, 2019 - frontiersin.org
The present study reports alterations of task-based functional brain connectivity in a group of
11 cosmonauts after a long-duration spaceflight, compared to a healthy control group not …

The effects of long duration spaceflight on sensorimotor control and cognition

GD Tays, KE Hupfeld, HR McGregor… - Frontiers in neural …, 2021 - frontiersin.org
Astronauts returning from spaceflight typically show transient declines in mobility and
balance. Other sensorimotor behaviors and cognitive function have not been investigated as …