Association mapping in plants in the post-GWAS genomics era
PK Gupta, PL Kulwal, V Jaiswal - Advances in genetics, 2019 - Elsevier
With the availability of DNA-based molecular markers during early 1980s and that of
sophisticated statistical tools in late 1980s and later, it became possible to identify genomic …
sophisticated statistical tools in late 1980s and later, it became possible to identify genomic …
Functional and genomic context in pathway analysis of GWAS data
Gene set analysis (GSA) is a promising tool for uncovering the polygenic effects associated
with complex diseases. However, the available techniques reflect a wide variety of …
with complex diseases. However, the available techniques reflect a wide variety of …
Linking disease associations with regulatory information in the human genome
Genome-wide association studies have been successful in identifying single nucleotide
polymorphisms (SNPs) associated with a large number of phenotypes. However, an …
polymorphisms (SNPs) associated with a large number of phenotypes. However, an …
Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease
Background Alzheimer's disease (AD) is one of the leading genetically complex and
heterogeneous disorder that is influenced by both genetic and environmental factors. The …
heterogeneous disorder that is influenced by both genetic and environmental factors. The …
Comparison of EMG signals recorded by surface electrodes on endotracheal tube and thyroid cartilage during monitored thyroidectomy
A variety of electromyography (EMG) recording methods were reported during intraoperative
neural monitoring (IONM) of recurrent laryngeal nerve (RLN) in thyroid surgery. This study …
neural monitoring (IONM) of recurrent laryngeal nerve (RLN) in thyroid surgery. This study …
GLiMMPS: robust statistical model for regulatory variation of alternative splicing using RNA-seq data
To characterize the genetic variation of alternative splicing, we develop GLiMMPS, a robust
statistical method for detecting splicing quantitative trait loci (sQTLs) from RNA-seq data …
statistical method for detecting splicing quantitative trait loci (sQTLs) from RNA-seq data …
TASUKE+: a web-based platform for exploring GWAS results and large-scale resequencing data
M Kumagai, D Nishikawa, Y Kawahara… - DNA …, 2019 - academic.oup.com
Recent revolutionary advancements in sequencing technologies have made it possible to
obtain mass quantities of genome-scale sequence data in a cost-effective manner and have …
obtain mass quantities of genome-scale sequence data in a cost-effective manner and have …
Phylomedicine: an evolutionary telescope to explore and diagnose the universe of disease mutations
Modern technologies have made the sequencing of personal genomes routine. They have
revealed thousands of nonsynonymous (amino acid altering) single nucleotide variants …
revealed thousands of nonsynonymous (amino acid altering) single nucleotide variants …
ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework
K Zhang, S Chang, S Cui, L Guo, L Zhang… - Nucleic acids …, 2011 - academic.oup.com
Genome-wide association study (GWAS) is widely utilized to identify genes involved in
human complex disease or some other trait. One key challenge for GWAS data interpretation …
human complex disease or some other trait. One key challenge for GWAS data interpretation …